PNN / Pinin

pinin, desmosome associated protein

Transcriptional activator binding to the E-box 1 core sequence of the E-cadherin promoter gene; the core-binding sequence is 5'CAGGTG-3'. Capable of reversing CTBP1-mediated transcription repression. Auxiliary component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junction on mRNAs. The EJC is a dynamic structure consisting of core proteins and several peripheral nuclear and cytoplasmic associated factors that join the complex only transiently either during EJC assembly or during subsequent mRNA metabolism. Participates in the regulation of alternative pre-mRNA splicing. Associates to spliced mRNA within 60 nt upstream of the 5'-splice sites. Component of the PSAP complex which binds RNA in a sequence-independent manner and is proposed to be recruited to the EJC prior to or during the splicing process and to regulate specific excision of introns in specific transcription subsets. Involved in the establishment and maintenance of epithelia cell-cell adhesion. Potential tumor suppressor for renal cell carcinoma.

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Proteins (3)

Type

Over-Expression Lysate (2)

Recombinant (1)

Target

PNN / Pinin (3)

Publications

No (3)

Tag

GST, N-terminus (1)

Myc-DDK (Flag) (2)

Species

Human (2)

Source

293T Cells (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

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Human PNN / Pinin Protein (Recombinant GST, N-terminus) (aa201-300) - LS-G59659

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PNN / Pinin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78061

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

81.4 kDa

Price:

20 µg/$150

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PNN / Pinin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117820

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

81.4 kDa

Price:

100 µg/$494

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