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PNMT

phenylethanolamine N-methyltransferase

PNMT catalyzes the last step of the catecholamine biosynthesis pathway, which methylates norepinephrine to form epinephrine (adrenaline). The enzyme also has beta-carboline 2N-methyltransferase activity. This gene is thought to play a key step in regulating epinephrine production. Alternatively spliced transcript variants have been found for this gene.

Gene Name:	phenylethanolamine N-methyltransferase
Synonyms:	PNMT, PNMTase, PENT, Phenylethanolamine N-methylase
Target Sequences:	NM_002686 NP_002677.1 P11086

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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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