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PLXNB3 / Plexin B3

Plexin B3

Receptor for SEMA5A that plays a role in axon guidance, invasive growth and cell migration. Stimulates neurite outgrowth and mediates Ca2+/Mg2+-dependent cell aggregation. In glioma cells, SEMA5A stimulation of PLXNB3 results in the disassembly of F-actin stress fibers, disruption of focal adhesions and cellular collapse as well as inhibition of cell migration and invasion through ARHGDIA-mediated inactivation of RAC1.

Gene Name: Plexin B3
Synonyms: PLXNB3, Plexin 6, Plexin B3, KIAA1206, PLEXB3, Plexin-B3, PLEXR, PLXN6
Target Sequences: NM_005393 NP_005384.2 Q9ULL4

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Proteins (2)
Over-Expression Lysate (2)
PLXNB3 / Plexin B3 (2)
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Myc-DDK (Flag) (2)
Human (1)
293T Cells (1)
HEK 293 Cells (1)
PLXNB3 / Plexin B3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
209.1 kDa
20 µg/$215
PLXNB3 / Plexin B3 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
209.1 kDa
100 µg/$710
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).