PLXNB2 / Plexin B2

plexin B2

Cell surface receptor for SEMA4C, SEMA4D and SEMA4G that plays an important role in cell-cell signaling. Binding to class 4 semaphorins promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal differentiation and migration of neuronal cells during brain corticogenesis and for normal embryonic brain development. Regulates the migration of cerebellar granule cells in the developing brain. Plays a role in RHOA activation and subsequent changes of the actin cytoskeleton. Plays a role in axon guidance, invasive growth and cell migration. May modulate the activity of RAC1 and CDC42. Down-regulates macrophage migration in wound-healing assays (in vitro).

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Products

Proteins (2)

Type

Recombinant (2)

Target

PLXNB2 / Plexin B2 (2)

Publications

No (2)

Tag

GST (1)

GST, N-terminus (1)

Species

Human (2)

Source

Wheat Germ Extract (2)

Purification

Purified (1)

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Human PLXNB2 / Plexin B2 Protein (Recombinant GST) (Full Length) - LS-G32942

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

77.33 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PLXNB2 / Plexin B2 Protein (Recombinant GST, N-terminus) (aa1506-1611) - LS-G62057

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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