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PLXNA4 / Plexin A4
plexin A4
Coreceptor for SEMA3A. Necessary for signaling by class 3 semaphorins and subsequent remodeling of the cytoskeleton. Plays a role in axon guidance in the developing nervous system. Class 3 semaphorins bind to a complex composed of a neuropilin and a plexin. The plexin modulates the affinity of the complex for specific semaphorins, and its cytoplasmic domain is required for the activation of down-stream signaling events in the cytoplasm.
| Gene Name: | plexin A4 |
| Synonyms: | PLXNA4, KIAA1550, PLXNA4A, Plexin A4, A, Plexin-A4, PLXNA4B, Plexin A4, Plexin A4, B, FAYV2820, PLEXA4, PRO34003 |
| Target Sequences: | NP_861440.2 Q9HCM2 |
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