PLIN5 / OXPAT / LSDP5

perilipin 5

Lipid droplet-associated protein that maintains the balance between lipogenesis and lipolysis and also regulates fatty acid oxidation in oxidative tissues. Recruits mitochondria to the surface of lipid droplets and is involved in lipid droplet homeostasis by regulating both the storage of fatty acids in the form of triglycerides and the release of fatty acids for mitochondrial fatty acid oxidation. In lipid droplet triacylglycerol hydrolysis, plays a role as a scaffolding protein for three major key lipolytic players: ABHD5, PNPLA2 and LIPE. Reduces the triacylglycerol hydrolase activity of PNPLA2 by recruiting and sequestering PNPLA2 to lipid droplets. Phosphorylation by PKA enables lipolysis probably by promoting release of ABHD5 from the perilipin scaffold and by facilitating interaction of ABHD5 with PNPLA2. Also increases lipolysis through interaction with LIPE and upon PKA-mediated phosphorylation of LIPE.

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Products

Proteins (2)

Type

Over-Expression Lysate (2)

Target

PLIN5 / OXPAT / LSDP5 (2)

Publications

No (2)

Tag

Myc-DDK (Flag) (2)

Species

Human (1)

Source

293T Cells (1)

HEK 293 Cells (1)

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Human PLIN5 / OXPAT / LSDP5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G93201

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.2 kDa

Price:

20 µg/$150

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PLIN5 / OXPAT / LSDP5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121542

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

51.2 kDa

Price:

100 µg/$494

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