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PLIN1 / Perilipin

perilipin 1

Modulator of adipocyte lipid metabolism. Coats lipid storage droplets to protect them from breakdown by hormone-sensitive lipase (HSL). Its absence may result in leanness. Plays a role in unilocular lipid droplet formation by activating CIDEC. Their interaction promotes lipid droplet enlargement and directional net neutral lipid transfer. May modulate lipolysis and triglyceride levels.

Gene Name: perilipin 1
Synonyms: PLIN1, FPLD4, PERI, Perilipin-1, PLIN, Perilipin, Perilipin 1
Target Sequences: NM_002666 NP_002657.3 O60240

Publications (2)

1
Evolutionarily conserved gene family important for fat storage. Kadereit B, Kumar P, Wang WJ, Miranda D, Snapp EL, Severina N, Torregroza I, Evans T, Silver DL. Proceedings of the National Academy of Sciences of the United States of America. 2008 105:94-9. [PubMed:18160536] [PMC:PMC2224239]
2
Expression of perilipin in human promyelocytic cells in response to Anaplasma phagocytophilum infection results in modified lipid metabolism. Manzano-Roman R, Almazn C, Naranjo V, Blouin EF, Kocan KM, de la Fuente J. Journal of medical microbiology. 2008 57:159-63. [PubMed:18201980]

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Products
Proteins (8)
Over-Expression Lysate (4)
Recombinant (4)
PLIN1 / Perilipin (8)
No (8)
6His, N-terminus (1)
GST, N-terminus (1)
His-GST, N-terminus (1)
Myc-DDK (Flag) (5)
Human (7)
Mouse (1)
293T Cells (2)
E. coli (1)
HEK 293 Cells (3)
Wheat Germ Extract (1)
Yeast (1)
Purified (2)
PLIN1 / Perilipin Protein - Recombinant Perilipin 1 (PLIN1) by SDS-PAGE
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E. coli
His-GST, N-terminus
52.4kDa
10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998
PLIN1 / Perilipin Protein - Purified recombinant protein PLIN1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
55.8 kDa
20 µg/$1,107
PLIN1 / Perilipin Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PLIN1 / Perilipin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
55.8 kDa
20 µg/$150
PLIN1 / Perilipin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
55.8 kDa
20 µg/$150
PLIN1 / Perilipin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Yeast
6His, N-terminus
11.2kDa
100 µg/$499; 20 µg/$364; 1 mg/$1,683
PLIN1 / Perilipin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
55.8 kDa
100 µg/$494
PLIN1 / Perilipin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
55.8 kDa
100 µg/$494
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).