PLCZ1

Phospholipase C, Zeta 1

The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. In vitro, hydrolyzes PtdIns(4,5)P2 in a Ca2+-dependent manner. Triggers intracellular Ca2+ oscillations in oocytes solely during M phase and is involved in inducing oocyte activation and initiating embryonic development up to the blastocyst stage. Is therefore a strong candidate for the egg-activating soluble sperm factor that is transferred from the sperm into the egg cytoplasm following gamete membrane fusion. May exert an inhibitory effect on phospholipase-C-coupled processes that depend on calcium ions and protein kinase C, including CFTR trafficking and function.

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Proteins (1)

Type

Recombinant (1)

Target

PLCZ1 (1)

Publications

No (1)

Tag

His-SUMO (1)

Species

Human (1)

Source

E. coli (1)

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Human PLCZ1 Protein (Recombinant His-SUMO) (Full Length) - LS-G21770

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

63.7 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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