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PLCL1
phospholipase C-like 1
Involved in an inositol phospholipid-based intracellular signaling cascade. Shows no PLC activity to phosphatidylinositol 4,5-bisphosphate and phosphatidylinositol. Component in the phospho-dependent endocytosis process of GABA A receptor By similarity. Regulates the turnover of receptors and thus contributes to the maintenance of GABA-mediated synaptic inhibition. Its aberrant expression could contribute to the genesis and progression of lung carcinoma. Acts as a inhibitor of PPP1C.
| Gene Name: | phospholipase C-like 1 |
| Family/Subfamily: | Phospholipase , not assigned-Phospholipase |
| Synonyms: | PLCL1, Phospholipase C, epsilon, PRIP, Phospholipase c, PLDL1, Phospholipase C-like 1, PLC-L, PLC-L1, PLCE, PLCL |
| Target Sequences: | NM_006226 |
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