PLCD4

phospholipase C, delta 4

Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca2+ from intracellular stores. Required for acrosome reaction in sperm during fertilization, probably by acting as an important enzyme for intracellular Ca2+ mobilization in the zona pellucida-induced acrosome reaction. May play a role in cell growth. Modulates the liver regeneration in cooperation with nuclear PKC. Overexpression up-regulates the Erk signaling pathway and proliferation.

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Products

Proteins (10)

Type

Over-Expression Lysate (2)

Recombinant (8)

Target

PLCD4 (10)

Publications

No (10)

Tag

GST (2)

GST, N-terminus (1)

His-SUMO (1)

His-T7, N-terminus (2)

Myc-DDK (Flag) (3)

Species

Human (7)

Mouse (1)

Rat (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (3)

Purification

Purified (3)

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Rat PLCD4 Protein (Recombinant His-T7, N-terminus) (Met1-Asp250) - LS-G133586

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

33.4kDa

Price:

10 µg/$273; 50 µg/$392; 200 µg/$782; 100 µg/$625; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029

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PLCD4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108657

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

87.4 kDa

Price:

100 µg/$494

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Human PLCD4 Protein (Recombinant His-SUMO) (Full Length) - LS-G21933

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

103.53 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PLCD4 Protein (Recombinant GST) (Full Length) - LS-G35827

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

109.34 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PLCD4 Protein (Recombinant GST) (Full Length) - LS-G35828

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

114 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PLCD4 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68652

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

87.4 kDa

Price:

20 µg/$1,107

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Human PLCD4 Protein (Recombinant GST, N-terminus) (aa18-127) - LS-G63407

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PLCD4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G82703

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

87.4 kDa

Price:

20 µg/$150

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Mouse PLCD4 Protein (Recombinant His-T7, N-terminus) (Met1-Asp250) - LS-G133508

Source:

E. coli

Tag:

His-T7, N-terminus

Molecular Weight:

33.2kDa

Price:

10 µg/$271; 50 µg/$382; 200 µg/$762; 100 µg/$610; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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Human PLCD4 Protein (Recombinant) (Met1-Asp250) - LS-G133653

Source:

E. coli

Tag:

None

Molecular Weight:

32.8kDa

Price:

10 µg/$284; 50 µg/$462; 200 µg/$922; 100 µg/$737; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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