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Membrane-associated phospholipase. Exhibits a calcium-independent broad substrate specificity including phospholipase A2/lysophospholipase activity. Preferential hydrolysis at the sn-2 position of diacylphospholipids and diacyglycerol, whereas it shows no positional specificity toward triacylglycerol. Exhibits also esterase activity toward p-nitrophenyl. May act on the brush border membrane to facilitate the absorption of digested lipids.
Gene Name: | Phospholipase B1 |
Synonyms: | PLB1, PLB, Phospholipase B/lipase, Phospholipase B, PLB/LIP |
Target Sequences: | NM_153021 NP_694566.4 Q6P1J6 |
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