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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PLAU / Urokinase / uPA

plasminogen activator, urokinase

PLAU / Urokinase / uPA is a serine protease involved in degradation of the extracellular matrix and possibly tumor cell migration and proliferation. A specific polymorphism in this gene may be associated with late-onset Alzheimer's disease and also with decreased affinity for fibrin-binding. This protein converts plasminogen to plasmin by specific cleavage of an Arg-Val bond in plasminogen. Plasmin in turn cleaves this protein at a Lys-Ile bond to form a two-chain derivative in which a single disulfide bond connects the amino-terminal A-chain to the catalytically active, carboxy-terminal B-chain. This two-chain derivative is also called HMW-uPA (high molecular weight uPA). HMW-uPA can be further processed into LMW-uPA (low molecular weight uPA) by cleavage of chain A into a short chain A (A1) and an amino-terminal fragment. LMW-uPA is proteolytically active but does not bind to the uPA receptor. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Gene Name: plasminogen activator, urokinase
Family/Subfamily: Protease , Serine S1
Synonyms: PLAU, BDPLT5, U-PA, U-plasminogen activator, URK, Urokinase, Plasminogen activator, urinary, QPD, UPA
Target Sequences: NM_002658 NP_002649.1 P00749

Filtered By: None
Target
PLAU / Urokinase / uPA (147)
Reactivity
Human (83)
Mouse (33)
Rat (23)
Chimpanzee (3)
Dog (10)
Gibbon (3)
Orangutan (3)
Pig (10)
Rabbit (4)
Application
IHC (61)
IHC-Fr (17)
IHC-P (18)
WB (129)
Flo (6)
DB (4)
ELISA (94)
Func (1)
ICC (4)
IF (7)
IP (1)
Peptide-ELISA (1)
RIA (4)
Host
rabbit (85)
mouse (37)
goat (3)
sheep (22)
Isotype
IgG (90)
IgG1 (25)
IgG1,k (2)
IgG2a (3)
Clonality
monoclonal mc (37)
polyclonal pc (110)
Clone
10D7.2 (1)
14 SCU-PA (1)
1D4 (1)
2G6.2 (1)
3B8 (1)
4 UK (1)
5H4 (1)
6H1 (1)
6H4 (1)
7- 18 (1)
724-3A1-8 (1)
724-3G6-5 (1)
H77A1 (1)
H77A10 (1)
H77B6 (1)
PGM2001 (2)
PGM2005 (2)
U-12 (1)
U-5 (1)
U-6 (2)
Format
AP Conjugated (5)
APC (3)
APC Conjugated (8)
Biotin Conjugated (20)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (20)
HRP Conjugated (10)
PE Conjugated (8)
Unconjugated (70)
Epitope
aa17-432 (10)
aa180-433 (10)
aa21-168 (10)
aa396-426 (8)
N-Terminus (6)
C-Terminus (4)
aa107-379 (4)
Internal (1)
Leu239 (1)
aa190-239 (1)
aa304-331 (1)
Publications
No (147)
Showing 1-25 of 147 results

PLAU / Urokinase / uPA Antibody (aa180-433) IHC-plus™ LS-B15016
Rabbit Polyclonal (IgG) to Mouse PLAU / Urokinase / uPA
Mouse
IHC IHC-P WB
Unconjugated
100µl 0.5mg/ml  $425.00
Human Tonsil, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot of recombinant PLAU / Urokinase / uPA.
Human Tonsil, Vessels: Formalin-Fixed, Paraffin-Embedded (FFPE)
Western blot of recombinant PLAU / Urokinase / uPA.

PLAU / Urokinase / uPA Antibody LS-C150831
Rabbit Polyclonal (IgG) to Mouse PLAU / Urokinase / uPA
Mouse, Rat
ELISA IHC IHC-Fr WB
Unconjugated
100µg 0.9mg/ml  $515.00

PLAU / Urokinase / uPA Antibody LS-C122523
Goat Polyclonal (IgG) to Human PLAU / Urokinase / uPA
Human
ELISA IHC IHC-Fr IHC-P RIA WB
Unconjugated
500µg  $560.00

PLAU / Urokinase / uPA Antibody (aa396-426) LS-C100932
Rabbit Polyclonal to Human PLAU / Urokinase / uPA
Human
Flo IF IHC IHC-P WB
Unconjugated
400µl  $305.00
Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with PLAU antibody (C-term ), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Confocal immunofluorescence of Urokinase (PLAU) Antibody with A2058 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).
Formalin-fixed and paraffin-embedded human prostate carcinoma tissue reacted with PLAU antibody (C-term ), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Confocal immunofluorescence of Urokinase (PLAU) Antibody with A2058 cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).

PLAU / Urokinase / uPA Antibody LS-C150828
Rabbit Polyclonal (IgG) to Mouse PLAU / Urokinase / uPA
Mouse, Rat
ELISA IHC IHC-Fr IHC-P WB
Unconjugated
1ml  $365.00

PLAU / Urokinase / uPA Antibody (clone 724-3A1-8) LS-C150850
Mouse Monoclonal [clone 724-3A1-8] (IgG) to Human PLAU / Urokinase / uPA
Human
ELISA WB
Unconjugated
1mg 2mg/ml  $465.00

PLAU / Urokinase / uPA Antibody (aa107-379, clone 5H4) LS-C339513
Mouse Monoclonal [clone 5H4] (IgG2a) to Human PLAU / Urokinase / uPA
Human
IHC IHC-P WB
Unconjugated
100µl 1mg/ml  $335.00
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PLAU mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-PLAU mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PLAU mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).
IHC of paraffin-embedded Carcinoma of Human lung tissue using anti-PLAU mouse monoclonal antibody. (Heat-induced epitope retrieval by 1 mM EDTA in 10mM Tris, pH8.5, 120°C for 3min).

PLAU / Urokinase / uPA Antibody LS-C122522
Rabbit Polyclonal (IgG) to Human PLAU / Urokinase / uPA
Human
ELISA IHC IHC-Fr IHC-P RIA WB
Unconjugated
500µg  $560.00

PLAU / Urokinase / uPA Antibody LS-C150841
Rabbit Polyclonal (IgG) to Rat PLAU / Urokinase / uPA
Rat
ELISA IHC IHC-Fr IHC-P WB
Unconjugated
100µg 0.74mg/ml  $515.00

PLAU / Urokinase / uPA Antibody (Biotin) LS-C124761
Rabbit Polyclonal to Human PLAU / Urokinase / uPA
Human
ELISA IHC WB
Biotin Conjugated
1000µg 7.35mg/ml  $725.00

PLAU / Urokinase / uPA Antibody (FITC) LS-C124762
Rabbit Polyclonal (IgG) to Human PLAU / Urokinase / uPA
Human
ELISA IHC WB
FITC Conjugated
1000µg 7.4mg/ml  $725.00

PLAU / Urokinase / uPA Antibody LS-C132821
Rabbit Polyclonal to Mouse PLAU / Urokinase / uPA
Mouse
ELISA WB
Unconjugated
200µg 7.5mg/ml  $485.00

PLAU / Urokinase / uPA Antibody (N-Terminus, clone 10D7.2) LS-C40102
Mouse Monoclonal [clone 10D7.2] (IgG2a) to Human PLAU / Urokinase / uPA
Human
ELISA WB
Unconjugated
100µg 1mg/ml  $710.00

PLAU / Urokinase / uPA Antibody LS-C150963
Sheep Polyclonal (IgG) to Mouse PLAU / Urokinase / uPA
Mouse, Rat
ELISA WB
Unconjugated
1mg 13.7mg/ml  $315.00

PLAU / Urokinase / uPA Antibody (clone 4 UK) LS-C40100
Mouse Monoclonal [clone 4 UK] (IgG1) to Human PLAU / Urokinase / uPA
Human
ELISA
Unconjugated
500µg 500µl 1mg/ml  $620.00

PLAU / Urokinase / uPA Antibody (aa396-426) LS-C330728
Rabbit Polyclonal (IgG) to Human PLAU / Urokinase / uPA
Human
ELISA Flo IF IHC WB
Unconjugated
200µl  $530.00

PLAU / Urokinase / uPA Antibody (aa396-426, AP) LS-C284082
Rabbit Polyclonal (IgG) to Human PLAU / Urokinase / uPA
Human
ELISA Flo IF IHC WB
AP Conjugated
200µl  $680.00

PLAU / Urokinase / uPA Antibody (aa396-426, APC) LS-C284083
Rabbit Polyclonal (IgG) to Human PLAU / Urokinase / uPA
Human
ELISA Flo IF IHC WB
APC Conjugated
200µl  $680.00

PLAU / Urokinase / uPA Antibody (aa396-426, PE) LS-C284085
Rabbit Polyclonal (IgG) to Human PLAU / Urokinase / uPA
Human
ELISA Flo IF IHC WB
PE Conjugated
200µl  $680.00

PLAU / Urokinase / uPA Antibody (N-Terminus, clone 7- 18) LS-C93254
Mouse Monoclonal [clone 7- 18] (IgG1) to Human PLAU / Urokinase / uPA
Human
Flo IF IHC IHC-Fr
Unconjugated
100µl 1mg/ml  $495.00

PLAU / Urokinase / uPA Antibody LS-C661451
Rabbit Polyclonal (IgG) to Human PLAU / Urokinase / uPA
Mouse, Rat, Human
ELISA IF IHC IP WB
Unconjugated
100µg 2mg/ml  $405.00

PLAU / Urokinase / uPA Antibody (N-Terminus, clone U-12) LS-C93255
Mouse Monoclonal [clone U-12] (IgG1) to Human PLAU / Urokinase / uPA
Human
ELISA IHC IHC-Fr WB
Unconjugated
100µl 1mg/ml  $495.00

PLAU / Urokinase / uPA Antibody (N-Terminus, clone U-5) LS-C93257
Mouse Monoclonal [clone U-5] (IgG1) to Human PLAU / Urokinase / uPA
Human
ELISA IHC IHC-Fr WB
Unconjugated
100µl 1mg/ml  $495.00

PLAU / Urokinase / uPA Antibody (N-Terminus, clone U-6) LS-C93256
Mouse Monoclonal [clone U-6] (IgG1) to Human PLAU / Urokinase / uPA
Human
ELISA IHC IHC-Fr WB
Unconjugated
100µl 1mg/ml  $495.00

PLAU / Urokinase / uPA Antibody (clone PGM2001) LS-C124756
Mouse Monoclonal [clone PGM2001] (IgG1) to Human PLAU / Urokinase / uPA
Human
ELISA IHC IHC-Fr RIA WB
Unconjugated
1000µl  $590.00
Showing 1-25 of 147 results

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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