PLA2R / PLA2R1

phospholipase A2 receptor 1, 180kDa

Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phosholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells. In neutrophils, binding of sPLA2-IB/PLA2G1B can activate p38 MAPK to stimulate elastase release and cell adhesion. May be involved in responses in proinflammatory cytokine productions during endotoxic shock. Also has endocytic properties and rapidly internalizes sPLA2 ligands, which is particularly important for the clearance of extracellular sPLA2s to protect their potent enzymatic activities. The soluble secretory phospholipase A2 receptor form is circulating and acts as a negative regulator of sPLA2 functions by blocking the biological functions of sPLA2-IB/PLA2G1B.

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Products

Antibodies (27)

Type

Primary (27)

Target

PLA2R / PLA2R1 (27)

Reactivity

Human (19)

Mouse (10)

Rat (2)

Monkey (1)

Application

IHC (2)

WB (22)

Flo (1)

ELISA (6)

Peptide-ELISA (1)

Host

rabbit (26)

goat (1)

Isotype

IgG (7)

Clonality

polyclonal pc (27)

Format

APC (2)

APC Conjugated (2)

Biotin Conjugated (3)

Cy3 Conjugated (2)

Cy7 Conjugated (2)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (2)

Unconjugated (10)

Epitope

aa1418-1487 (8)

aa385-643 (8)

aa395-530 (4)

C-Terminus (2)

aa946-957 (1)

Publications

No (26)

Yes (1)

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PLA2R / PLA2R1 Antibody (C-Terminus) LS-C153547

(4.0) Rating

(1) Publication(s)

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µg/$440; 100 µg/$480

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PLA2R / PLA2R1 Antibody (aa946-957) LS-C108906

Antibody:

PLA2R / PLA2R1 Goat anti-Human Polyclonal (aa946-957) Antibody

Reactivity:

Human, Monkey

Applications:

Flo, Peptide-ELISA

Format:

Unconjugated

Price:

100 µg/$503

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PLA2R / PLA2R1 Antibody (aa1418-1487) LS-C374775

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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PLA2R / PLA2R1 Antibody (aa1418-1487, HRP) LS-C712800

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (HRP) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$342; 200 µl/$398; 500 µl/$585; 1 ml/$722; 2 ml/$959; 5 ml/$1,639

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PLA2R / PLA2R1 Antibody (aa1418-1487, Biotin) LS-C688138

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (Biotin) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$321; 200 µl/$369; 500 µl/$527; 1 ml/$611; 2 ml/$842; 5 ml/$1,387

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PLA2R / PLA2R1 Antibody (aa1418-1487, FITC) LS-C695050

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (FITC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$352; 200 µl/$412; 500 µl/$622; 1 ml/$777; 2 ml/$1,014; 5 ml/$1,765

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PLA2R / PLA2R1 Antibody (aa1418-1487, Cy3) LS-C703776

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (Cy3) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

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PLA2R / PLA2R1 Antibody (aa1418-1487, APC) LS-C718460

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (APC) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

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PLA2R / PLA2R1 Antibody (aa1418-1487, PE) LS-C726857

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (PE) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$412; 200 µl/$499; 500 µl/$869; 1 ml/$1,030; 2 ml/$1,345; 5 ml/$2,521

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PLA2R / PLA2R1 Antibody (aa1418-1487, APC, Cy7) LS-C735781

Antibody:

PLA2R / PLA2R1 Rabbit anti-Mouse Polyclonal (aa1418-1487) (APC, Cy7) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

APC, Cy7 Conjugated

Price:

100 µl/$513; 200 µl/$666; 500 µl/$1,175; 1 ml/$1,441; 2 ml/$2,017; 5 ml/$3,781

• Unconjugated
• HRP
• Biotin
• FITC
• Cy3
• APC
• PE
• More...
  • APC, Cy7

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • Cy3
  • APC
  • PE
  • APC, Cy7

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PLA2R / PLA2R1 Antibody LS-C668183

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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PLA2R / PLA2R1 Antibody LS-C676271

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

50 µl/$294; 100 µl/$360

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PLA2R / PLA2R1 Antibody LS-C496781

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PLA2R / PLA2R1 Antibody LS-C832802

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

Select

PLA2R / PLA2R1 Antibody (C-Terminus) LS-C144967

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

200 µl/$468

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PLA2R / PLA2R1 Antibody (aa395-530) LS-C371409

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa395-530) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PLA2R / PLA2R1 Antibody (aa395-530, HRP) LS-C371410

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa395-530) (HRP) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

PLA2R / PLA2R1 Antibody (aa395-530, Biotin) LS-C371416

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa395-530) (Biotin) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

Select

PLA2R / PLA2R1 Antibody (aa395-530, FITC) LS-C371408

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa395-530) (FITC) Antibody

Reactivity:

Human

Applications:

ELISA

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PLA2R / PLA2R1 Antibody (aa385-643) LS-C295908

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$309; 200 µl/$351; 500 µl/$491; 1 ml/$561; 2 ml/$755; 5 ml/$1,225

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PLA2R / PLA2R1 Antibody (aa385-643, HRP) LS-C712795

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) (HRP) Antibody

Reactivity:

Human

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$338; 200 µl/$393; 500 µl/$575; 1 ml/$702; 2 ml/$939; 5 ml/$1,593

Select

PLA2R / PLA2R1 Antibody (aa385-643, Biotin) LS-C688139

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) (Biotin) Antibody

Reactivity:

Human

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$319; 200 µl/$365; 500 µl/$519; 1 ml/$596; 2 ml/$824; 5 ml/$1,348

Select

PLA2R / PLA2R1 Antibody (aa385-643, FITC) LS-C302476

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) (FITC) Antibody

Reactivity:

Human

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$348; 200 µl/$407; 500 µl/$605; 1 ml/$755; 2 ml/$993; 5 ml/$1,716

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PLA2R / PLA2R1 Antibody (aa385-643, PE) LS-C726856

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) (PE) Antibody

Reactivity:

Human

Applications:

WB

Format:

PE Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008

Select

PLA2R / PLA2R1 Antibody (aa385-643, Cy3) LS-C703777

Antibody:

PLA2R / PLA2R1 Rabbit anti-Human Polyclonal (aa385-643) (Cy3) Antibody

Reactivity:

Human

Applications:

WB

Format:

Cy3 Conjugated

Price:

100 µl/$407; 200 µl/$491; 500 µl/$850; 1 ml/$1,008; 2 ml/$1,308; 5 ml/$2,451

• Unconjugated
• HRP
• Biotin
• FITC
• PE
• Cy3

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • PE
  • Cy3

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