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Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PLA2R / PLA2R1

phospholipase A2 receptor 1, 180kDa

Receptor for secretory phospholipase A2 (sPLA2). Acts as a receptor for phosholipase sPLA2-IB/PLA2G1B but not sPLA2-IIA/PLA2G2A. Also able to bind to snake PA2-like toxins. Although its precise function remains unclear, binding of sPLA2 to its receptor participates in both positive and negative regulation of sPLA2 functions as well as clearance of sPLA2. Binding of sPLA2-IB/PLA2G1B induces various effects depending on the cell type, such as activation of the mitogen-activated protein kinase (MAPK) cascade to induce cell proliferation, the production of lipid mediators, selective release of arachidonic acid in bone marrow-derived mast cells. In neutrophils, binding of sPLA2-IB/PLA2G1B can activate p38 MAPK to stimulate elastase release and cell adhesion. May be involved in responses in proinflammatory cytokine productions during endotoxic shock. Also has endocytic properties and rapidly internalizes sPLA2 ligands, which is particularly important for the clearance of extracellular sPLA2s to protect their potent enzymatic activities. The soluble secretory phospholipase A2 receptor form is circulating and acts as a negative regulator of sPLA2 functions by blocking the biological functions of sPLA2-IB/PLA2G1B.

Gene Name: phospholipase A2 receptor 1, 180kDa
Family/Subfamily: Phospholipase , not assigned-Phospholipase
Synonyms: PLA2R1, CLEC13C, M-type receptor, PLA2IR, PLA2-R, PLA2G1R, PLA2R
Target Sequences: NM_007366 NP_031392.3 Q13018

Filtered By: None
Target
PLA2R / PLA2R1 (31)
Reactivity
Human (20)
Mouse (11)
Rat (1)
Monkey (1)
Application
IHC (20)
IHC-P (8)
WB (26)
Flo (1)
ELISA (7)
ICC (2)
Peptide-ELISA (1)
Host
rabbit (29)
mouse (1)
goat (1)
Isotype
IgG (25)
IgG1,k (1)
Clonality
monoclonal mc (1)
polyclonal pc (30)
Clone
600000000 (1)
Format
APC (2)
APC Conjugated (2)
Biotin Conjugated (5)
Cy3 Conjugated (2)
Cy7 Conjugated (2)
FITC Conjugated (4)
HRP Conjugated (3)
PE Conjugated (2)
Unconjugated (11)
Epitope
aa1418-1487 (10)
aa385-643 (9)
aa395-530 (4)
C-Terminus (2)
aa946-957 (1)
Publications
No (31)
Showing 1-25 of 31 results

PLA2R / PLA2R1 Antibody (aa385-643) LS-C295908
Rabbit Polyclonal (IgG) to Human PLA2R / PLA2R1
Human
IHC WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $255.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $530.00; 10ml 0.5mg/ml  $2,100.00
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PLA2R / PLA2R1 Antibody (aa385-643, HRP) LS-C712795
Rabbit Polyclonal (IgG) to Human PLA2R / PLA2R1
Human
IHC WB
HRP Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $345.00; 1ml  $680.00; 10ml  $2,730.00
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PLA2R / PLA2R1 Antibody (aa385-643, Biotin) LS-C300190
Rabbit Polyclonal (IgG) to Human PLA2R / PLA2R1
Human
WB
Biotin Conjugated
100µl 0.5mg/ml  $375.00
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PLA2R / PLA2R1 Antibody (aa385-643, Biotin) LS-C688139
Rabbit Polyclonal (IgG) to Human PLA2R / PLA2R1
Human
IHC WB
Biotin Conjugated
20µl  $205.00; 100µl  $265.00; 200µl  $315.00; 1ml  $575.00; 10ml  $2,310.00
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PLA2R / PLA2R1 Antibody (aa385-643, FITC) LS-C302476
Rabbit Polyclonal (IgG) to Human PLA2R / PLA2R1
Human
IHC WB
FITC Conjugated
100µl 0.5mg/ml  $455.00
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PLA2R / PLA2R1 Antibody (aa385-643, Cy3) LS-C703777
Rabbit Polyclonal (IgG) to Human PLA2R / PLA2R1
Human
IHC WB
Cy3 Conjugated
20µl  $245.00; 100µl  $355.00; 200µl  $445.00; 1ml  $1,050.00; 10ml  $4,200.00
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PLA2R / PLA2R1 Antibody (aa385-643, PE) LS-C726856
Rabbit Polyclonal (IgG) to Human PLA2R / PLA2R1
Human
IHC WB
PE Conjugated
20µl  $215.00; 100µl  $275.00; 200µl  $325.00; 1ml  $635.00; 10ml  $2,520.00
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PLA2R / PLA2R1 Antibody (aa385-643, APC) LS-C741203
Rabbit Polyclonal (IgG) to Human PLA2R / PLA2R1
Human
IHC WB
APC Conjugated
20µl  $225.00; 100µl  $305.00; 200µl  $375.00; 1ml  $785.00
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
Western blot of recombinant PLA2R / PLA2R1.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PLA2R / PLA2R1 Antibody (C-Terminus) LS-C153547
Rabbit Polyclonal to Human PLA2R / PLA2R1
Human
ELISA IHC WB
Unconjugated
100µg 100µl 1mg/ml  $345.00

PLA2R / PLA2R1 Antibody (aa1418-1487) LS-C374775
Rabbit Polyclonal (IgG) to Mouse PLA2R / PLA2R1
Mouse
IHC IHC-P WB
Unconjugated
20µl 0.5mg/ml  $205.00; 100µl 0.5mg/ml  $265.00; 200µl 0.5mg/ml  $305.00; 1ml 0.5mg/ml  $545.00; 10ml 0.5mg/ml  $2,160.00
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

PLA2R / PLA2R1 Antibody (aa1418-1487, HRP) LS-C712800
Rabbit Polyclonal (IgG) to Mouse PLA2R / PLA2R1
Mouse
IHC IHC-P WB
HRP Conjugated
20µl  $215.00; 100µl  $295.00; 200µl  $345.00; 1ml  $695.00; 10ml  $2,805.00
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

PLA2R / PLA2R1 Antibody (aa1418-1487, Biotin) LS-C688138
Rabbit Polyclonal (IgG) to Mouse PLA2R / PLA2R1
Mouse
IHC IHC-P WB
Biotin Conjugated
20µl  $205.00; 100µl  $275.00; 200µl  $315.00; 1ml  $590.00; 10ml  $2,370.00
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

PLA2R / PLA2R1 Antibody (aa1418-1487, Biotin) LS-C423343
Rabbit Polyclonal (IgG) to Mouse PLA2R / PLA2R1
Mouse
ICC WB
Biotin Conjugated
100µl 0.5mg/ml  $375.00

PLA2R / PLA2R1 Antibody (aa1418-1487, FITC) LS-C695050
Rabbit Polyclonal (IgG) to Mouse PLA2R / PLA2R1
Mouse
IHC IHC-P WB
FITC Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $335.00; 1ml  $650.00; 10ml  $2,580.00
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

PLA2R / PLA2R1 Antibody (aa1418-1487, FITC) LS-C423346
Rabbit Polyclonal (IgG) to Mouse PLA2R / PLA2R1
Mouse
ICC WB
FITC Conjugated
100µl 0.5mg/ml  $395.00

PLA2R / PLA2R1 Antibody (aa1418-1487, PE) LS-C726857
Rabbit Polyclonal (IgG) to Mouse PLA2R / PLA2R1
Mouse
IHC IHC-P WB
PE Conjugated
20µl  $215.00; 100µl  $285.00; 200µl  $335.00; 1ml  $650.00; 10ml  $2,580.00
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

PLA2R / PLA2R1 Antibody (aa1418-1487, APC) LS-C718460
Rabbit Polyclonal (IgG) to Mouse PLA2R / PLA2R1
Mouse
IHC IHC-P WB
APC Conjugated
20µl  $225.00; 100µl  $315.00; 200µl  $375.00; 1ml  $815.00; 10ml  $3,600.00
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

PLA2R / PLA2R1 Antibody (aa1418-1487, APC, Cy7) LS-C735781
Rabbit Polyclonal (IgG) to Mouse PLA2R / PLA2R1
Mouse
IHC IHC-P WB
APC, Cy7 Conjugated
20µl  $285.00; 100µl  $465.00; 200µl  $650.00; 1ml  $1,620.00; 10ml  $6,480.00
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

PLA2R / PLA2R1 Antibody (aa1418-1487, Cy3) LS-C703776
Rabbit Polyclonal (IgG) to Mouse PLA2R / PLA2R1
Mouse
IHC IHC-P WB
Cy3 Conjugated
20µl  $245.00; 100µl  $365.00; 200µl  $445.00; 1ml  $1,080.00; 10ml  $4,320.00
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Lung, Respiratory Epithelium: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)

PLA2R / PLA2R1 Antibody (aa946-957) LS-C108906
Goat Polyclonal to Human PLA2R / PLA2R1
Human, Monkey
Flo Peptide-ELISA
Unconjugated
100µg 0.5mg/ml  $405.00
PLA2R1 antibody (1 ug/ml) staining of Human Ileum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Approx 150kDa band observed in Human Kidney and Pig Lung lysates (calculated MW of 153kDa according to NP_001007268.1). Recommended concentration: 1-3µg/ml.
PLA2R1 antibody (1 ug/ml) staining of Human Ileum lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
Approx 150kDa band observed in Human Kidney and Pig Lung lysates (calculated MW of 153kDa according to NP_001007268.1). Recommended concentration: 1-3µg/ml.

PLA2R / PLA2R1 Antibody LS-C144652
Rabbit Polyclonal to Human PLA2R / PLA2R1
Human
IHC WB
Unconjugated
100µl  $365.00

PLA2R / PLA2R1 Antibody (C-Terminus) LS-C144967
Rabbit Polyclonal to Human PLA2R / PLA2R1
Human
IHC WB
Unconjugated
100µl  $365.00

PLA2R / PLA2R1 Antibody LS-C496781
Rabbit Polyclonal (IgG) to Human PLA2R / PLA2R1
Mouse, Rat, Human
IHC WB
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00
Immunohistochemistry of paraffin-embedded rat liver using PLA2R1 antibodyat dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using PLA2R1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Immunohistochemistry of paraffin-embedded rat liver using PLA2R1 antibodyat dilution of 1:100 (40x lens).
Western blot analysis of extracts of various cell lines, using PLA2R1 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.

PLA2R / PLA2R1 Antibody LS-C676271
Rabbit Polyclonal (IgG) to Human PLA2R / PLA2R1
Human
ELISA WB
Unconjugated
50µl  $235.00; 100µl  $285.00
Western blot All Lanes: PLA2R1 antibody IgG at 0.78ug/ml+ Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 169,153 kDa Observed band size: 169 kDa
Western blot All Lanes: PLA2R1 antibody IgG at 0.78ug/ml+ Jurkat whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 169,153 kDa Observed band size: 169 kDa

PLA2R / PLA2R1 Antibody (clone 600000000) LS-C742092
Mouse Monoclonal [clone 600000000] (IgG1,k)
ELISA WB
Unconjugated
40µg  $245.00
Western Blot validation of Human PLA2R1 Antibody (6E8) with Human PLA2R1 recombinant protein. Lane 1: 50 ng Human PLA2R1 recombinant protein Lane 2: 25 ng Human PLA2R1 recombinant protein Lane 3: 10 ng Human PLA2R1 recombinant protein Primary Antibody: Human PLA2R1 Antibody (6E8) 1 µg/ml Secondary Antibody: Goat anti-Mouse IgG (H&L) [IRDye8°°] (Licor,926-32211)00.125 µg/ml
ELISA binding of Human PLA2R1 Antibody (6E8) with Human PLA2R1 recombinant protein. Coating antigen: PLA2R1, 1 µg/ml. PLA2R1 antibody dilutions start from 1000 ng/ml, EC50= 53.12 ng/ml.
Western Blot validation of Human PLA2R1 Antibody (6E8) with Human PLA2R1 recombinant protein. Lane 1: 50 ng Human PLA2R1 recombinant protein Lane 2: 25 ng Human PLA2R1 recombinant protein Lane 3: 10 ng Human PLA2R1 recombinant protein Primary Antibody: Human PLA2R1 Antibody (6E8) 1 µg/ml Secondary Antibody: Goat anti-Mouse IgG (H&L) [IRDye8°°] (Licor,926-32211)00.125 µg/ml
ELISA binding of Human PLA2R1 Antibody (6E8) with Human PLA2R1 recombinant protein. Coating antigen: PLA2R1, 1 µg/ml. PLA2R1 antibody dilutions start from 1000 ng/ml, EC50= 53.12 ng/ml.
Showing 1-25 of 31 results

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For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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