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PLA2G2A / SPLA2

phospholipase A2, group IIA (platelets, synovial fluid)

PLA2G2A / SPLA2 is a member of the phospholipase A2 family (PLA2). PLA2s constitute a diverse family of enzymes with respect to sequence, function, localization, and divalent cation requirements. This gene product belongs to group II, which contains secreted form of PLA2, an extracellular enzyme that has a low molecular mass and requires calcium ions for catalysis. It catalyzes the hydrolysis of the sn-2 fatty acid acyl ester bond of phosphoglycerides, releasing free fatty acids and lysophospholipids, and thought to participate in the regulation of the phospholipid metabolism in biomembranes. Several alternatively spliced transcript variants with different 5' UTRs have been found for this gene.

Gene Name: phospholipase A2, group IIA (platelets, synovial fluid)
Family/Subfamily: Phospholipase , not assigned-Phospholipase
Synonyms: PLA2G2A, GIIC sPLA2, Group IIA phospholipase A2, MOM1, PLA2L, PLA2S, NPS-PLA2, PLAS1, PLA2, PLA2B, RASF-A, SPLA2
Target Sequences: NM_000300 NP_000291.1

Publications (1)

1
Plasma apolipopotein C-2 elevation is associated with Takayasu arteritis. Natsuko Tamura, Yasuhiro Maejima, Yuka Shiheido-Watanabe, Shun Nakagama, Mitsuaki Isobe , Tetsuo Sasano. Scientific reports. 2021 Sep;11:18958. [Full Text Article] [PubMed:34556808] [PMC:PMC8460645]

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Products
Proteins (17)
Over-Expression Lysate (8)
Recombinant (9)
PLA2G2A / SPLA2 (17)
No (17)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
His (2)
His, N-Terminal (1)
His-GST (1)
His-SUMO (1)
Myc-DDK (Flag) (9)
Human (10)
Rat (3)
293T Cells (4)
E. coli (4)
HEK 293 Cells (6)
Wheat Germ Extract (2)
Yeast (1)
Purified (3)
Low endotoxin level (1)
PLA2G2A / SPLA2 Protein - Recombinant Phospholipase A2, Group IIA By SDS-PAGE
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E. coli
His, N-Terminal
17.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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HEK 293 Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
15.4 kDa
50 µg/$710
PLA2G2A / SPLA2 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PLA2G2A / SPLA2 Protein - Purified recombinant protein PLA2G2A was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
13.9 kDa
20 µg/$1,107
PLA2G2A / SPLA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
16.08 kDa
20 µg/$150
PLA2G2A / SPLA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
16.08 kDa
20 µg/$150
PLA2G2A / SPLA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
16.08 kDa
20 µg/$150
PLA2G2A / SPLA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
16.08 kDa
20 µg/$150
PLA2G2A / SPLA2 Protein - Recombinant Phospholipase A2, Group IIA By SDS-PAGE
Select
E. coli
His-GST
46.5 kDa
10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
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Yeast
His
16.1 kD
100 µg/$499; 20 µg/$364; 1 mg/$1,683
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E. coli
His-SUMO
30.1 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
PLA2G2A / SPLA2 Protein - 12.5% SDS-PAGE of human PLA2G2A stained with Coomassie Blue
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Wheat Germ Extract
GST
42.5 kDa
2 µg/$439
PLA2G2A / SPLA2 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
17.9kDa
1 mg/$1,355; 100 µg/$420; 20 µg/$323
PLA2G2A / SPLA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
16.08 kDa
100 µg/$494
PLA2G2A / SPLA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
16.08 kDa
100 µg/$494
PLA2G2A / SPLA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
16.08 kDa
100 µg/$494
PLA2G2A / SPLA2 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
16.08 kDa
100 µg/$494
Viewing 1-17 of 17 product results


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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).