PKD2 / Polycystin 2

polycystic kidney disease 2 (autosomal dominant)

Functions as a calcium permeable cation channel involved in fluid-flow mechanosensation by the primary cilium in renal epithelium. PKD1 and PKD2 may function through a common signaling pathway that is necessary for normal tubulogenesis. Acts as a regulator of cilium length, together with PKD1. The dynamic control of cilium length is essential in the regulation of mechanotransductive signaling. The cilium length response creates a negative feedback loop whereby fluid shear-mediated deflection of the primary cilium, which decreases intracellular cAMP, leads to cilium shortening and thus decreases flow-induced signaling. Also involved in left/right axis specification downstream of nodal flow: forms a complex with PKD2 in cilia to facilitate flow detection in left/right patterning.

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Products

Antibodies (27)

Type

Primary (27)

Target

PKD2 / Polycystin 2 (27)

Reactivity

Human (22)

Mouse (18)

Rat (4)

Bat (1)

Bovine (1)

Chimpanzee (3)

Dog (1)

Gibbon (3)

Guinea pig (3)

Hamster (1)

Horse (1)

Monkey (4)

Orangutan (3)

Rabbit (3)

Xenopus (1)

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Application

IHC (2)

IHC-P (2)

WB (20)

ELISA (12)

IF (4)

IP (2)

Peptide-ELISA (3)

Host

rabbit (25)

mouse (1)

goat (1)

Isotype

IgG (17)

IgG2a,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (26)

Clone

4C8 (1)

Format

APC Conjugated (1)

Azide-free (1)

Biotin Conjugated (3)

FITC Conjugated (3)

HRP Conjugated (3)

PE Conjugated (1)

Unconjugated (16)

Epitope

aa874-903 (7)

aa196-245 (4)

750-830 aa (1)

C-Terminus (1)

aa871-883 (1)

aa918-968 (1)

aa937-968 (1)

pSer812 (1)

Publications

No (27)

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PKD2 / Polycystin 2 Antibody LS-C332683

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PKD2 / Polycystin 2 Antibody (clone 4C8) LS-C197911

Antibody:

PKD2 / Polycystin 2 Mouse anti-Human Monoclonal (4C8) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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PKD2 / Polycystin 2 Antibody (aa871-883) LS-C108143

Antibody:

PKD2 / Polycystin 2 Goat anti-Human Polyclonal (aa871-883) Antibody

Reactivity:

Xenopus, Bat, Hamster, Horse, Mouse, Dog, Bovine, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µg/$503

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PKD2 / Polycystin 2 Antibody (aa196-245) LS-C201302

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (aa196-245) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PKD2 / Polycystin 2 Antibody (aa196-245, HRP) LS-C432042

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (aa196-245) (HRP) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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PKD2 / Polycystin 2 Antibody (aa196-245, Biotin) LS-C432040

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (aa196-245) (Biotin) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PKD2 / Polycystin 2 Antibody (aa196-245, FITC) LS-C432041

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (aa196-245) (FITC) Antibody

Reactivity:

Rabbit, Mouse, Guinea pig, Human, Monkey, Chimpanzee, Orangutan, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PKD2 / Polycystin 2 Antibody (aa937-968) LS-C99725

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (aa937-968) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

400 µl/$393

Select

PKD2 / Polycystin 2 Antibody LS-C742578

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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PKD2 / Polycystin 2 Antibody (C-Terminus) LS-C46906

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

0.1 mg/$379

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PKD2 / Polycystin 2 Antibody LS-C671693

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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PKD2 / Polycystin 2 Antibody (Biotin) LS-C671698

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• Biotin

• Unconjugated
• Biotin

Select

PKD2 / Polycystin 2 Antibody (750-830 aa) LS-C381782

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (750-830 aa) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IF

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

Select

PKD2 / Polycystin 2 Antibody LS-C753062

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$331

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PKD2 / Polycystin 2 Antibody (phospho-Ser812) LS-C291179

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (pSer812) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

PKD2 / Polycystin 2 Antibody (aa874-903) LS-C329976

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (aa874-903) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

Select

PKD2 / Polycystin 2 Antibody (aa874-903, Biotin) LS-C266429

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Mouse Polyclonal (aa874-903) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

Select

PKD2 / Polycystin 2 Antibody (aa874-903, FITC) LS-C266427

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Mouse Polyclonal (aa874-903) (FITC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

PKD2 / Polycystin 2 Antibody (aa874-903, APC) LS-C266426

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Mouse Polyclonal (aa874-903) (APC) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

Select

PKD2 / Polycystin 2 Antibody (aa874-903, Azide-free, HRP) LS-C266428

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Mouse Polyclonal (aa874-903) (Azide-free) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

HRP Conjugated, Azide-free

Price:

200 µl/$952

Select

PKD2 / Polycystin 2 Antibody (aa874-903, PE) LS-C266430

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Mouse Polyclonal (aa874-903) (PE) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

PE Conjugated

Price:

200 µl/$952

• Unconjugated
• Biotin
• FITC
• APC
• HRP, Azide-free
• PE

• Unconjugated
• Biotin
• FITC
• More...
  • APC
  • HRP, Azide-free
  • PE

Select

PKD2 / Polycystin 2 Antibody (aa918-968) LS-C289206

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (aa918-968) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

PKD2 / Polycystin 2 Antibody LS-C802533

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

Select

PKD2 / Polycystin 2 Antibody (aa874-903) LS-C163746

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal (aa874-903) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Select

PKD2 / Polycystin 2 Antibody LS-C668163

Antibody:

PKD2 / Polycystin 2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

50 µl/$286; 100 µl/$321

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