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PIP4K2A / PIPK

phosphatidylinositol-5-phosphate 4-kinase, type II, alpha

Catalyzes the phosphorylation of phosphatidylinositol 5-phosphate (PtdIns5P) on the fourth hydroxyl of the myo-inositol ring, to form phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May exert its function by regulating the levels of PtdIns5P, which functions in the cytosol by increasing AKT activity and in the nucleus signals through ING2. May regulate the pool of cytosolic PtdIns5P in response to the activation of tyrosine phosphorylation. May negatively regulate insulin-stimulated glucose uptake by lowering the levels of PtdIns5P. May be involved in thrombopoiesis, and the terminal maturation of megakaryocytes and regulation of their size.

Gene Name: phosphatidylinositol-5-phosphate 4-kinase, type II, alpha
Family/Subfamily: Non-Protein Kinase , not assigned-Non-Protein Kinase
Synonyms: PIP4K2A, PI(5)P 4-kinase type II alpha, PIP5KII-alpha, PIP5KIII, PIPK, PtdIns(4)P-5-kinase B isoform, PtdIns(4)P-5-kinase C isoform, PI5P4KA, PIP4KII-alpha, PIP5K2, PIP5KIIalpha, PIP5K2A, PIP5KIIA
Target Sequences: NM_005028 NP_005019.2 P48426

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Products
Proteins (7)
Over-Expression Lysate (2)
Recombinant (5)
PIP4K2A / PIPK (7)
No (7)
6His, C-terminus (2)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (3)
Human (6)
293T Cells (1)
HEK 293 Cells (2)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (2)
Purified (1)
Low endotoxin level (2)
PIP4K2A / PIPK Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PIP4K2A / PIPK Protein - Purified recombinant protein PIP4K2A was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
46 kDa
20 µg/$1,107
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Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
47.3kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
PIP4K2A / PIPK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
46 kDa
20 µg/$150
PIP4K2A / PIPK Protein - 12.5% SDS-PAGE of human PIP5K2A stained with Coomassie Blue
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Wheat Germ Extract
GST
70.4 kDa
10 µg/$479; 25 µg/$670
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Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
47.3 kDa
10 µg/$317; 50 µg/$524
PIP4K2A / PIPK Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
46 kDa
100 µg/$494
Viewing 1-7 of 7 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).