PIK3R5

phosphoinositide-3-kinase, regulatory subunit 5

Phosphatidylinositol 3-kinases (PI3Ks) phosphorylate the inositol ring of phosphatidylinositol at the 3-prime position, and play important roles in cell growth, proliferation, differentiation, motility, survival and intracellular trafficking. The PI3Ks are divided into three classes: I, II and III, and only the class I PI3Ks are involved in oncogenesis. This gene encodes the 101 kD regulatory subunit of the class I PI3K gamma complex, which is a dimeric enzyme, consisting of a 110 kD catalytic subunit gamma and a regulatory subunit of either 55, 87 or 101 kD. This protein recruits the catalytic subunit from the cytosol to the plasma membrane through high-affinity interaction with G-beta-gamma proteins. Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found.

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Proteins (6)

Type

Over-Expression Lysate (4)

Recombinant (2)

Target

PIK3R5 (6)

Publications

No (6)

Tag

GST (1)

His-SUMO (1)

Myc-DDK (Flag) (4)

Species

Human (4)

Source

293T Cells (2)

E. coli (1)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PIK3R5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89925

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.2 kDa

Price:

20 µg/$215

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PIK3R5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G126059

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.2 kDa

Price:

100 µg/$710

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Human PIK3R5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89927

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.2 kDa

Price:

20 µg/$215

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Human PIK3R5 Protein (Recombinant His-SUMO) (Full Length) - LS-G21835

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

70.84 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PIK3R5 Protein (Recombinant GST) (Full Length) - LS-G32877

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

81.3 kDa

Price:

2 µg/$439

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PIK3R5 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G101194

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

97.2 kDa

Price:

100 µg/$710

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