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PIGO is a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid which contains three mannose molecules in its core backbone. The GPI-anchor is found on many blood cells and serves to anchor proteins to the cell surface. This protein is involved in the transfer of ethanolaminephosphate (EtNP) to the third mannose in GPI. At least three alternatively spliced transcripts encoding two distinct isoforms have been found for this gene.
Gene Name: | phosphatidylinositol glycan anchor biosynthesis, class O |
Synonyms: | PIGO, HPMRS2, PIG-O, RP11-182N22.4 |
Target Sequences: | BC001030 AAH01030.1 |
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