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PIDD1

p53-induced death domain protein

PIDD1 contains a leucine-rich repeat and a death domain. This protein has been shown to interact with other death domain proteins, such as Fas (TNFRSF6)-associated via death domain (FADD) and MAP-kinase activating death domain-containing protein (MADD), and thus may function as an adaptor protein in cell death-related signaling processes. The expression of the mouse counterpart of this gene has been found to be positively regulated by the tumor suppressor p53 and to induce cell apoptosis in response to DNA damage, which suggests a role for this gene as an effector of p53-dependent apoptosis. Alternative splicing results in multiple transcript variants.

Gene Name: p53-induced death domain protein
Synonyms: PIDD1, LRDD, PIDD
Target Sequences: NM_018494 NP_665893.2 Q9HB75

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Proteins (5)
Over-Expression Lysate (2)
Recombinant (3)
PIDD1 (5)
No (5)
His-T7 (3)
Myc-DDK (Flag) (2)
Human (2)
Mouse (1)
Rat (1)
293T Cells (1)
E. coli (3)
HEK 293 Cells (1)
PIDD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
97.6 kDa
100 µg/$494
PIDD1 Protein - Recombinant Leucine Rich Repeats And Death Domain Containing Protein By SDS-PAGE
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E. coli
His-T7
25.2 kDa
10 µg/$272; 50 µg/$387; 100 µg/$620; 200 µg/$772; 1 mg/$1,834; 500 µg/$1,393; 5 mg/$2,794; 2 mg/$2,016
PIDD1 Protein - Recombinant Leucine Rich Repeats And Death Domain Containing Protein By SDS-PAGE
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E. coli
His-T7
31.5 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
PIDD1 Protein - Recombinant Leucine Rich Repeats And Death Domain Containing Protein By SDS-PAGE
Select
E. coli
His-T7
31.7 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
PIDD1 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
97.6 kDa
20 µg/$150
Viewing 1-5 of 5 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).