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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

TCR Screening Services

Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PICK1

protein interacting with PRKCA 1

Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.

Gene Name: protein interacting with PRKCA 1
Synonyms: PICK1, DJ1039K5, PRKCABP, Protein interacting with PRKCA, PRKCA-binding protein, PICK
Target Sequences: NM_012407 NP_036539.1 Q9NRD5

Publications (1)

1
Interaction between the glutamate transporter GLT1b and the synaptic PDZ domain protein PICK1. Bassan M, Liu H, Madsen KL, Armsen W, Zhou J, Desilva T, Chen W, Paradise A, Brasch MA, Staudinger J, Gether U, Irwin N, Rosenberg PA. The European journal of neuroscience. 2008 27:66-82. [PubMed:18184314]

Filtered by: None
Target
PICK1 (49)
Reactivity
Human (37)
Mouse (36)
Rat (20)
Bovine (3)
Chicken (2)
Dog (2)
Guinea pig (1)
Hamster (2)
Horse (1)
Monkey (3)
Orangutan (1)
Pig (1)
Rabbit (1)
Xenopus (1)
Application
IHC (15)
IHC-P (5)
WB (46)
ELISA (22)
ICC (1)
IF (9)
IP (6)
Peptide-ELISA (1)
Host
rabbit (44)
goat (1)
chicken (4)
Isotype
IgG (26)
IgY (4)
Clonality
polyclonal pc (49)
Format
AP Conjugated (2)
APC (1)
APC Conjugated (3)
Azide-free (2)
Biotin Conjugated (6)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (3)
Unconjugated (20)
Epitope
C-Terminus (9)
aa1-30 (8)
aa24-229 (8)
aa286-316 (8)
aa100-110 (1)
Publications
No (49)
Showing 1-25 of 49 results

IHC-plus™ PICK1 Antibody (aa100-110) LS-B15948
Goat Polyclonal to Human PICK1
Xenopus, Chicken, Bovine, Rat, Hamster, Pig, Horse, Rabbit, Mouse, Dog, Human, Monkey
IHC-P, Peptide-ELISA, WB
Unconjugated
50µg 0.5mg/ml  $425.00
Human Colon: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)

PICK1 Antibody LS-C754054
Rabbit Polyclonal (IgG) to Human PICK1
Human
ELISA, IF, IHC, IP, WB
Unconjugated
100µg  $335.00

PICK1 Antibody LS-C331510
Rabbit Polyclonal (IgG) to Human PICK1
Human
IF, IHC, WB
Unconjugated
50µl  $235.00; 100µl  $315.00; 200µl  $425.00
Immunohistochemistry of paraffin-embedded human colon tissue.
Immunohistochemistry of paraffin-embedded human prostate.

PICK1 Antibody LS-C355513
Rabbit Polyclonal (IgG) to Human PICK1
Chicken, Bovine, Mouse, Dog, Guinea pig, Rat, Hamster, Orangutan, Human, Monkey
ICC, IF, IP, WB
Unconjugated
100µg  $445.00
IF using PICK1 Antibody
WB using PICK1 Antibody

PICK1 Antibody LS-C285648
Rabbit Polyclonal (IgG) to Human PICK1
Human
ELISA, IHC, WB
Unconjugated
50µg  $285.00; 100µg  $385.00
Immunohistochemistry of paraffin-embedded human breast cancer using PICK1 Antibody at dilution of 1:100
Immunohistochemistry of paraffin-embedded human rectum tissue using PICK1 Antibody at dilution of 1:100

PICK1 Antibody (HRP) LS-C370621
Rabbit Polyclonal (IgG) to Human PICK1
Human
ELISA, IHC, WB
HRP Conjugated
50µg  $285.00; 100µg  $385.00
Western blot. All lanes: Acid-sensing ion channel 3 antibody at 2 ug/ml+mouse brain tissue. Secondary antibody: goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PICK1 Antibody (Biotin) LS-C370623
Rabbit Polyclonal (IgG) to Human PICK1
Human
ELISA, IHC, WB
Biotin Conjugated
50µg  $285.00; 100µg  $385.00
Western blot. All lanes: Acid-sensing ion channel 3 antibody at 2 ug/ml+mouse brain tissue. Secondary antibody: goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PICK1 Antibody (FITC) LS-C370622
Rabbit Polyclonal (IgG) to Human PICK1
Human
ELISA, IHC, WB
FITC Conjugated
50µg  $285.00; 100µg  $385.00
Western blot. All lanes: Acid-sensing ion channel 3 antibody at 2 ug/ml+mouse brain tissue. Secondary antibody: goat polyclonal to Rabbit IgG at 1:10000 dilution. Predicted band size: 47 kDa. Observed band size: 47 kDa. This image was taken for the unconjugated form of this product. Other forms have not been tested.

PICK1 Antibody LS-C809512
Rabbit Polyclonal (IgG) to Human PICK1
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100µl 1mg/ml  $325.00; 200µl 1mg/ml  $375.00
Western blot Image

PICK1 Antibody LS-C748619
Rabbit Polyclonal (IgG) to Human PICK1
Human
IF, IHC
Unconjugated
50µl  $235.00; 100µl  $295.00; 200µl  $385.00

PICK1 Antibody LS-C769632
Rabbit Polyclonal (IgG) to Human PICK1
Human
IF, IHC
Unconjugated
60µl 1mg/ml  $235.00; 120µl 1mg/ml  $295.00; 200µl 1mg/ml  $395.00

PICK1 Antibody (C-Terminus, Biotin) LS-C143325
Chicken Polyclonal (IgY) to Rat PICK1
Mouse, Rat
IF, IHC, IHC-P, IP, WB
Biotin Conjugated
100µl  $365.00
PICK1 Antibody - IHC of PICK1 on mouse bladder.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PICK1 Antibody - Western blot of PICK1 expression in rat brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PICK1 Antibody (C-Terminus, DY488) LS-C143327
Chicken Polyclonal (IgY) to Rat PICK1
Mouse, Rat
IF, IHC, IHC-P, IP, WB
DY488 Conjugated
100µl  $365.00
PICK1 Antibody - IHC of PICK1 on mouse bladder.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PICK1 Antibody - Western blot of PICK1 expression in rat brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PICK1 Antibody (C-Terminus, DY550) LS-C143329
Chicken Polyclonal (IgY) to Rat PICK1
Mouse, Rat
IF, IHC, IHC-P, IP, WB
DY550 Conjugated
100µl  $365.00
PICK1 Antibody - IHC of PICK1 on mouse bladder.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PICK1 Antibody - Western blot of PICK1 expression in rat brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PICK1 Antibody (C-Terminus, DY650) LS-C143326
Chicken Polyclonal (IgY) to Rat PICK1
Mouse, Rat
IF, IHC, IHC-P, IP, WB
DY650 Conjugated
100µl  $365.00
PICK1 Antibody - IHC of PICK1 on mouse bladder.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
PICK1 Antibody - Western blot of PICK1 expression in rat brain lysate.  This image was taken for the unconjugated form of this product. Other forms have not been tested.

PICK1 Antibody LS-C193003
Rabbit Polyclonal to Human PICK1
Mouse, Rat, Human
IHC, WB
Unconjugated
100µl  $385.00
Western blot.

PICK1 Antibody LS-C405900
Rabbit Polyclonal (IgG) to Human PICK1
Mouse, Rat, Human
ELISA, IHC
Unconjugated
20µl 0.2mg/ml  $205.00; 60µl 0.2mg/ml  $235.00; 120µl 0.2mg/ml  $295.00; 200µl 0.2mg/ml  $395.00
Immunohistochemistry of paraffin-embedded Human liver cancer using PICK1 Polyclonal Antibody at dilution of 1:25.
Immunohistochemistry of paraffin-embedded Human liver cancer using PICK1 Polyclonal Antibody at dilution of 1:25.

PICK1 Antibody (aa1-30) LS-C328239
Rabbit Polyclonal (IgG) to Human PICK1
Mouse, Human
ELISA, WB
Unconjugated
200µl  $590.00

PICK1 Antibody (aa286-316) LS-C328236
Rabbit Polyclonal (IgG) to Human PICK1
Mouse, Human
ELISA, WB
Unconjugated
200µl  $590.00

PICK1 Antibody (aa286-316, Biotin) LS-C245321
Rabbit Polyclonal (IgG) to Human PICK1
Mouse, Human
ELISA, WB
Biotin Conjugated
200µl  $740.00

PICK1 Antibody (aa286-316, FITC) LS-C245322
Rabbit Polyclonal (IgG) to Human PICK1
Mouse, Human
ELISA, WB
FITC Conjugated
200µl  $740.00

PICK1 Antibody (aa286-316, AP) LS-C245319
Rabbit Polyclonal (IgG) to Human PICK1
Mouse, Human
ELISA, WB
AP Conjugated
200µl  $740.00

PICK1 Antibody (aa286-316, APC) LS-C245320
Rabbit Polyclonal (IgG) to Human PICK1
Mouse, Human
ELISA, WB
APC Conjugated
200µl  $740.00

PICK1 Antibody (aa286-316, PE) LS-C245323
Rabbit Polyclonal (IgG) to Human PICK1
Mouse, Human
ELISA, WB
PE Conjugated
200µl  $740.00

PICK1 Antibody LS-C779860
Rabbit Polyclonal to Human PICK1
Mouse, Rat, Human
ELISA, WB
Unconjugated
100µg 100µl 1mg/ml  $305.00
Showing 1-25 of 49 results

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).