PICK1

protein interacting with PRKCA 1

Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence. Involved in the clustering of various receptors, possibly by acting at the receptor internalization level. Plays a role in synaptic plasticity by regulating the trafficking and internalization of AMPA receptors. May be regulated upon PRKCA activation. May regulate ASIC1/ASIC3 channel. Regulates actin polymerization by inhibiting the actin-nucleating activity of the Arp2/3 complex; the function is competetive with nucleation promoting factors and is linked to neuronal morphology regulation and AMPA receptor (AMPAR) endocytosis. Via interaction with the Arp2/3 complex involved in regulation of synaptic plasicity of excitatory synapses and required for spine shrinkage during long-term depression (LTD). Involved in regulation of astrocyte morphology, antagonistic to Arp2/3 complex activator WASL/N-WASP function.

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Products

Proteins (17)

Type

Over-Expression Lysate (8)

Recombinant (9)

Target

PICK1 (17)

Publications

No (17)

Tag

GST (2)

GST, N-terminus (1)

His (1)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (11)

Species

Human (12)

Mouse (1)

Source

293T Cells (4)

E. coli (4)

HEK 293 Cells (7)

Wheat Germ Extract (2)

Purification

Purified (2)

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Human PICK1 Protein (Recombinant GST, N-terminus) (aa266-375) - LS-G61135

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PICK1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71427

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

20 µg/$1,107

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Human PICK1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71428

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

20 µg/$1,107

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Human PICK1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71429

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

20 µg/$1,107

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Human PICK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89737

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

20 µg/$150

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Human PICK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89739

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

20 µg/$150

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Human PICK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89738

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

20 µg/$150

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Human PICK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G89740

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

20 µg/$150

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Human PICK1 Protein (Recombinant His, N-Terminal) (Phe2-Ser415) - LS-G97030

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

50 kDa

Price:

10 µg/$265; 100 µg/$365; 50 µg/$315

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Mouse PICK1 Protein (Recombinant His-T7) (aa24-229) - LS-G13094

Source:

E. coli

Tag:

His-T7

Molecular Weight:

26.3 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Human PICK1 Protein (Recombinant GST) (Full Length) - LS-G22277

Source:

E. coli

Tag:

GST

Molecular Weight:

49.3 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human PICK1 Protein (Recombinant GST) (Full Length) - LS-G31646

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

73 kDa

Price:

10 µg/$479; 25 µg/$670

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PICK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G123781

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

100 µg/$494

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Human PICK1 Protein (Recombinant His) - LS-G3140

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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PICK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120630

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

100 µg/$494

Select

PICK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G120631

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

100 µg/$494

Select

PICK1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G114450

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.4 kDa

Price:

100 µg/$494

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