PIAS3

protein inhibitor of activated STAT, 3

Functions as an E3-type small ubiquitin-like modifier (SUMO) ligase, stabilizing the interaction between UBE2I and the substrate, and as a SUMO-tethering factor. Plays a crucial role as a transcriptional coregulation in various cellular pathways, including the STAT pathway and the steroid hormone signaling pathway. Involved in regulating STAT3 signaling via inhibiting STAT3 DNA-binding and suppressing cell growth. Enhances the sumoylation of MTA1 and may participate in its paralog-selective sumoylation.

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Products

Proteins (5)

Type

Over-Expression Lysate (2)

Recombinant (3)

Target

PIAS3 (5)

Publications

No (5)

Tag

GST (1)

GST, N-terminus (1)

His-GST (1)

Myc-DDK (Flag) (2)

Species

Human (4)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

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Human PIAS3 Protein (Recombinant GST, N-terminus) (aa453-550) - LS-G61495

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PIAS3 Protein (Recombinant His-GST) (aa11-280) - LS-G25479

Source:

E. coli

Tag:

His-GST

Molecular Weight:

59.9 kDa

Price:

10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148

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Human PIAS3 Protein (Recombinant GST) (Full Length) - LS-G32127

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

93.4 kDa

Price:

2 µg/$439

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Human PIAS3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G84006

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.8 kDa

Price:

20 µg/$150

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PIAS3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100723

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

67.8 kDa

Price:

100 µg/$494

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