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PI4KA is a phosphatidylinositol (PI) 4-kinase which catalyzes the first committed step in the biosynthesis of phosphatidylinositol 4,5-bisphosphate. The mammalian PI 4-kinases have been classified into two types, II and III, based on their molecular mass, and modulation by detergent and adenosine. The protein encoded by this gene is a type III enzyme that is not inhibited by adenosine.
Gene Name: | phosphatidylinositol 4-kinase, catalytic, alpha |
Family/Subfamily: | Non-Protein Kinase , not assigned-Non-Protein Kinase |
Synonyms: | PI4KA, PI4K-ALPHA, Pi4K230, PIK4CA, PI4-kinase alpha, PIK4, PtdIns-4-kinase alpha |
Target Sequences: | NM_002650 NP_002641.1 P42356 |
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