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B001/B101
Shirley, MA 01464
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20700 44th Avenue W
Lynnwood, WA 98036
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PHF5A / INI
PHD finger protein 5A
PHF5A / INI is a subunit of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP). The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. The protein encoded by this gene contains a PHD-finger-like domain that is flanked by highly basic N- and C-termini. This protein belongs to the PHD-finger superfamily and may act as a chromatin-associated protein. This gene has several pseudogenes on different chromosomes.
| Gene Name: | PHD finger protein 5A |
| Synonyms: | PHF5A, BK223H9.2, INI, PHD finger protein 5A, SF3b14b, PHD-finger 5a, Rds3, SAP14b |
| Target Sequences: | NM_032758 CAB62939.1 Q7RTV0 |
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