PHF2

PHD finger protein 2

Lysine demethylase that demethylates both histones and non-histone proteins. Enzymatically inactive by itself, and becomes active following phosphorylation by PKA: forms a complex with ARID5B and mediates demethylation of methylated ARID5B. Demethylation of ARID5B leads to target the PHF2-ARID5B complex to target promoters, where PHF2 mediates demethylation of dimethylated 'Lys-9' of histone H3 (H3K9me2), followed by transcription activation of target genes. The PHF2-ARID5B complex acts as a coactivator of HNF4A in liver. PHF2 is recruited to trimethylated 'Lys-4' of histone H3 (H3K4me3) at rDNA promoters and promotes expression of rDNA.

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Products

Antibodies (9)

Type

Primary (9)

Target

PHF2 (9)

Reactivity

Human (9)

Chimpanzee (3)

Gibbon (3)

Rabbit (3)

Application

IHC (2)

IHC-P (1)

WB (8)

ELISA (2)

IP (1)

Host

rabbit (8)

mouse (1)

Product Group

IHCPlus (1)

Isotype

IgG (3)

IgM,k (1)

Clonality

monoclonal mc (1)

polyclonal pc (8)

Clone

3E7 (1)

Format

Biotin Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

Preservative Free (1)

Unconjugated (6)

Epitope

aa936-985 (4)

aa650-700 (1)

Publications

No (9)

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IHC-plus™ PHF2 Antibody LS-B172

(4.0) Rating

Antibody:

PHF2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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PHF2 Antibody LS-C753511

Antibody:

PHF2 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, IP, WB

Format:

Unconjugated

Price:

100 µg/$351

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PHF2 Antibody (clone 3E7) LS-C197892

Antibody:

PHF2 Mouse anti-Human Monoclonal (3E7) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$423

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PHF2 Antibody (aa936-985) LS-C109733

Antibody:

PHF2 Rabbit anti-Human Polyclonal (aa936-985) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

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PHF2 Antibody (aa936-985, HRP) LS-C428934

Antibody:

PHF2 Rabbit anti-Human Polyclonal (aa936-985) (HRP) Antibody

Reactivity:

Rabbit, Human, Chimpanzee, Gibbon

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

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PHF2 Antibody (aa936-985, Biotin) LS-C428932

Antibody:

PHF2 Rabbit anti-Human Polyclonal (aa936-985) (Biotin) Antibody

Reactivity:

Rabbit, Human, Chimpanzee, Gibbon

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

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PHF2 Antibody (aa936-985, FITC) LS-C428933

Antibody:

PHF2 Rabbit anti-Human Polyclonal (aa936-985) (FITC) Antibody

Reactivity:

Rabbit, Human, Chimpanzee, Gibbon

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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PHF2 Antibody (aa650-700) LS-C290132

Antibody:

PHF2 Rabbit anti-Human Polyclonal (aa650-700) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

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PHF2 Antibody (Preservative Free) LS-C815683

Antibody:

PHF2 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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