PHF1

PHD finger protein 1

Polycomb group (PcG) that specifically binds histone H3 trimethylated at 'Lys-36' (H3K36me3) and recruits the PRC2 complex. Involved in DNA damage response and is recruited at double-strand breaks (DSBs). Acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex: it is however unclear whether recruitment of the PRC2 complex to H3K36me3 leads to enhance or inhibit H3K27me3 methylation mediated by the PRC2 complex. According to some reports, PRC2 recruitment by PHF1 promotes H3K27me3 and subsequent gene silencing by inducing spreading of PRC2 and H3K27me3 into H3K36me3 loci (PubMed:18285464 and PubMed:23273982). According to another report, PHF1 recruits the PRC2 complex at double-strand breaks (DSBs) and inhibits the activity of PRC2 (PubMed:23142980). Regulates p53/TP53 stability and prolonges its turnover: may act by specifically binding to a methylated from of p53/TP53.

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Antibodies (28)

Proteins (4)

ELISA Kits (3)

Type

Custom (1)

Over-Expression Lysate (2)

Primary (28)

Recombinant (2)

Sandwich (2)

Target

PHF1 (35)

Reactivity

Human (29)

Mouse (12)

Rat (13)

Bat (9)

Bovine (7)

Chimpanzee (3)

Dog (10)

Gibbon (9)

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Application

IHC (9)

IHC-P (1)

WB (27)

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ELISA (3)

ICC (1)

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Peptide-ELISA (2)

Host

rabbit (24)

mouse (4)

Isotype

IgG (18)

IgG1 (3)

IgG1,k (1)

Clonality

monoclonal mc (4)

polyclonal pc (24)

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864C6a (2)

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FITC Conjugated (3)

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Unconjugated (19)

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C-Terminus (5)

N-Terminus (4)

aa421-470 (4)

320-400 aa, Internal (1)

Internal (1)

Lys381 (1)

aa164-197 (1)

aa345-394 (1)

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No (35)

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Plasma (2)

Serum (2)

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Myc-DDK (Flag) (2)

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Source

293T Cells (1)

HEK 293 Cells (1)

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Purification

Purified (1)

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PHF1 Antibody LS-C409985

Antibody:

PHF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503

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PHF1 Antibody (Preservative Free) LS-C814976

Antibody:

PHF1 Rabbit anti-Human Polyclonal (Preservative Free) Antibody

Reactivity:

Human

Applications:

ICC, IF, WB

Format:

Unconjugated, Preservative Free

Price:

100 µl/$412

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PHF1 Antibody (320-400 aa, Internal) LS-C385472

Antibody:

PHF1 Rabbit anti-Human Polyclonal (320-400 aa, Internal) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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PHF1 Antibody LS-C800442

Antibody:

PHF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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PHF1 Antibody (Internal) LS-C368644

Antibody:

PHF1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Rabbit, Dog, Bovine, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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PHF1 Antibody (C-Terminus) LS-C144885

Antibody:

PHF1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$440; 200 µl/$468

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PHF1 Antibody (Lys381) LS-C192031

Antibody:

PHF1 Rabbit anti-Human Polyclonal (Lys381) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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PHF1 Antibody (aa421-470) LS-C31286

Antibody:

PHF1 Rabbit anti-Human Polyclonal (aa421-470) Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µl/$397

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PHF1 Antibody (aa421-470, HRP) LS-C428931

Antibody:

PHF1 Rabbit anti-Human Polyclonal (aa421-470) (HRP) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Rat, Pig, Bat, Gibbon, Human

Applications:

IHC, WB

Format:

HRP Conjugated

Price:

100 µl/$442

Select

PHF1 Antibody (aa421-470, Biotin) LS-C428929

Antibody:

PHF1 Rabbit anti-Human Polyclonal (aa421-470) (Biotin) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Rat, Pig, Bat, Gibbon, Human

Applications:

IHC, WB

Format:

Biotin Conjugated

Price:

100 µl/$442

Select

PHF1 Antibody (aa421-470, FITC) LS-C428930

Antibody:

PHF1 Rabbit anti-Human Polyclonal (aa421-470) (FITC) Antibody

Reactivity:

Rabbit, Dog, Guinea pig, Rat, Pig, Bat, Gibbon, Human

Applications:

IHC, WB

Format:

FITC Conjugated

Price:

100 µl/$442

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PHF1 Antibody (clone 2D3) LS-C197891

Antibody:

PHF1 Mouse anti-Human Monoclonal (2D3) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

Select

PHF1 Antibody LS-C822450

Antibody:

PHF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$357

Select

PHF1 Antibody (clone 864C6a) LS-C342699

Antibody:

PHF1 Mouse anti-Human Monoclonal (864C6a) Antibody

Reactivity:

Human

Applications:

DB, WB

Format:

Unconjugated

Price:

100 µg/$486

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PHF1 Antibody (aa345-394) LS-C118676

Antibody:

PHF1 Rabbit anti-Human Polyclonal (aa345-394) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

Select

PHF1 Antibody LS-C74823

Antibody:

PHF1 Mouse anti-Human Monoclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$786

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PHF1 Antibody (clone 864C6a) LS-C184669

Antibody:

PHF1 Mouse anti-Human Monoclonal (864C6a) Antibody

Reactivity:

Human

Applications:

DB

Format:

Unconjugated

Price:

100 µg/$965

Select

PHF1 Antibody (N-Terminus) LS-C80269

Antibody:

PHF1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PHF1 Antibody (N-Terminus, HRP) LS-C438870

Antibody:

PHF1 Rabbit anti-Human Polyclonal (N-Terminus) (HRP) Antibody

Reactivity:

Rabbit, Dog, Bovine, Horse, Bat, Gibbon, Human, Chimpanzee

Applications:

WB

Format:

HRP Conjugated

Price:

100 µl/$469

Select

PHF1 Antibody (N-Terminus, Biotin) LS-C438868

Antibody:

PHF1 Rabbit anti-Human Polyclonal (N-Terminus) (Biotin) Antibody

Reactivity:

Rabbit, Dog, Bovine, Horse, Bat, Gibbon, Human, Chimpanzee

Applications:

WB

Format:

Biotin Conjugated

Price:

100 µl/$469

Select

PHF1 Antibody (N-Terminus, FITC) LS-C438869

Antibody:

PHF1 Rabbit anti-Human Polyclonal (N-Terminus) (FITC) Antibody

Reactivity:

Rabbit, Dog, Bovine, Horse, Bat, Gibbon, Human, Chimpanzee

Applications:

WB

Format:

FITC Conjugated

Price:

100 µl/$469

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

Select

PHF1 Antibody (C-Terminus) LS-C80270

Antibody:

PHF1 Rabbit anti-Human Polyclonal (C-Terminus) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$424

Select

PHF1 Antibody LS-C416017

Antibody:

PHF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

50 µg/$305; 100 µg/$357

Select

PHF1 Antibody LS-C394177

Antibody:

PHF1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$386

Select

PHF1 Antibody (aa164-197) LS-C344267

Antibody:

PHF1 Rabbit anti-Human Polyclonal (aa164-197) Antibody

Reactivity:

Mouse

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

Viewing 1-25 of 35 product results

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