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PHB / Prohibitin

prohibitin

Prohibitin inhibits DNA synthesis. It has a role in regulating proliferation. As yet it is unclear if the protein or the mRNA exhibits this effect. May play a role in regulating mitochondrial respiration activity and in aging.

Gene Name: prohibitin
Synonyms: PHB, PHB1, Prohibitin
Target Sequences: NM_002634 NP_002625.1 P35232

Publications (4)

1
Coupling of the de novo fatty acid biosynthesis and lipoylation pathways in mammalian mitochondria. Witkowski A, Joshi AK, Smith S. The Journal of biological chemistry. 2007 282:14178-85. [PubMed:17374604]
2
Up-regulation of the peroxiredoxin-6 related metabolism of reactive oxygen species in skeletal muscle of mice lacking neuronal nitric oxide synthase. Da Silva-Azevedo L, Jhne S, Hoffmann C, Stalder D, Heller M, Pries AR, Zakrzewicz A, Baum O. The Journal of physiology. 2009 587:655-68. [PubMed:19047200] [PMC:PMC2670087]
3
Circulating levels of mitochondrial uncoupling protein 2, but not prohibitin, are lower in humans with type 2 diabetes and correlate with brachial artery flow-mediated dilation. Kakarla M, Puppala VK, Tyagi S, Anger A, Repp K, Wang J, Ying R, Widlansky ME. Cardiovascular Diabetology. 2019 November;18:148. [Full Text Article] [PubMed:31706320] [PMC:PMC6842161]
4
A proteomic view of isoproterenol induced cardiac hypertrophy: prohibitin identified as a potential biomarker in rats. Chowdhury D, Tangutur AD, Khatua TN, Saxena P, Banerjee SK, Bhadra MP. Journal of translational medicine. 2013 11:130. (IHC, WB; Human) [Full Text Article] [PubMed:23706090] [PMC:PMC3667141] Related Antibodies: LS-C29731.
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☰ Filters
Products
Proteins (8)
Over-Expression Lysate (2)
Recombinant (6)
PHB / Prohibitin (8)
No (8)
10His, N-terminus (2)
GST (1)
His (2)
Myc-DDK (Flag) (3)
Human (5)
Mouse (2)
293T Cells (1)
E. coli (4)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (4)
PHB / Prohibitin Protein - 12.5% SDS-PAGE of human PHB stained with Coomassie Blue
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Human PHB / Prohibitin Protein (Recombinant GST) (Full Length) - LS-G29720
Wheat Germ Extract
GST
55.66 kDa
10 µg/$479; 25 µg/$670
PHB / Prohibitin Protein - Based on the SEQUEST from database of E.coli host and target protein, the LC-MS/MS Analysis result of Recombinant Mouse Prohibitin(Phb),partial could indicate that this peptide derived from E.coli-expressed Mus musculus (Mouse) Phb.
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Mouse PHB / Prohibitin Protein (Recombinant 10His, N-terminus) - LS-G136407
E. coli
10His, N-terminus
20.5 kDa
20 µg/$405; 1 mg/$1,679; 100 µg/$598
PHB / Prohibitin Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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Mouse PHB / Prohibitin Protein (Recombinant 10His, N-terminus) - LS-G137088
E. coli
10His, N-terminus
16.2 kDa
1 mg/$1,679; 100 µg/$598; 20 µg/$405
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Human PHB / Prohibitin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88668
293T Cells
Myc-DDK (Flag)
29.6 kDa
20 µg/$150
PHB / Prohibitin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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PHB / Prohibitin Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117860
HEK 293 Cells
Myc-DDK (Flag)
29.6 kDa
100 µg/$494
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Human PHB / Prohibitin Protein (Recombinant His) (Full Length) - LS-G21047
E. coli
His
33.9 kD
1 mg/$1,355; 100 µg/$420; 20 µg/$323
PHB / Prohibitin Protein
Select
Human PHB / Prohibitin Protein (Recombinant His) - LS-G2204
E. coli
His
50 µg/$361; 250 µg/$739; 10 µg/$261
PHB / Prohibitin Protein - Purified recombinant protein PHB was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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Human PHB / Prohibitin Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G71065
HEK 293 Cells
Myc-DDK (Flag)
29.6 kDa
20 µg/$1,107
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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