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Immunohistochemistry Services

Work with LifeSpan to design a custom immunohistochemistry to address your specific biological question. Outsource the entire localization process without having to worry about finding and characterizing target specific antibodies, sourcing and validating difficult-to-find tissues, and having the ability to interpret the resulting immunostaining in relation to complex human pathologies.

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Test your therapeutic antibodies in immunohistochemistry against a broad panel of normal frozen human tissue types in order to determine potential unintended binding. Our non-GLP TCR services are designed on the FDA recommendation outlined in their "Points to Consider in the Manufacture and Testing of Monoclonal Antibody Products for Human Use".

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PHAP1 / ANP32A

acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.

Gene Name: acidic (leucine-rich) nuclear phosphoprotein 32 family, member A
Synonyms: ANP32A, Hepatopoietin Cn, I1PP2A, LANP, HPPCn, PHAP1, PHAPI, MAPM, PP32, C15orf1, Mapmodulin
Target Sequences: NM_006305 NP_006296.1 P39687

Publications (1)

1
Species difference in ANP32A underlies influenza A virus polymerase host restriction. Long JS, Giotis ES, Moncorgé O, Frise R, Mistry B, James J, Morisson M, Iqbal M, Vignal A, Skinner MA, Barclay WS. Nature. 2016 529:101-4. (WB; Human) [Full Text Article] [PubMed:26738596] [PMC:PMC4710677] Related Antibodies: LS-B10851.

Viewing 1-25 of 59 items
PHAP1 / ANP32A Antibody - Human, Colon: Formalin-Fixed Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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(1) Publication(s)
Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Xenopus, Chicken, Zebrafish, Horse, Dog, Guinea pig, Bovine, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $485.00
PHAP1 / ANP32A Antibody - Anti-ANP32A antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $545.00
PHAP1 / ANP32A Antibody - Anti-ANP32A antibody IHC of human liver. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Mouse Monoclonal [clone 2G11-4A5] (IgG1,k) to Human PHAP1 / ANP32A
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50µg   $495.00
PHAP1 / ANP32A Antibody - Anti-ANP32A antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50µg   1mg/ml   $545.00
PHAP1 / ANP32A Antibody - Anti-ANP32A antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Mouse, Rat, Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
0.05mg   1mg/ml   $425.00
PHAP1 / ANP32A Antibody - Anti-ANP32A rabbit polyclonal antibody at 1:500 dilution. Lane A: HEK293 Whole Cell Lysate. Lane B: Raji Whole Cell Lysate. Lane C: HeLa Whole Cell Lysate. Lane D: Jurkat Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 28 kDa. Observed band size: 28 kDa.
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Human
ELISA, ICC, IF, IHC-P, IP, WB
Unconjugated, Preservative Free
50µl   $235.00; 100µl   $275.00; 200µl   $305.00
PHAP1 / ANP32A Antibody - Immunocytochemistry of PHAP I in Raji cells with PHAP I antibody at 2 ug/ml.
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Mouse, Human
ELISA, ICC, IF, WB
Unconjugated
0.1mg   1mg/ml   $365.00
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Human
ELISA, IF, IHC, WB
Unconjugated
100µg   $405.00
PHAP1 / ANP32A Antibody - Immunohistochemistry of paraffin-embedded Human mammary cancer tissue.
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50µl   $235.00; 100µl   $315.00; 200µl   $425.00
PHAP1 / ANP32A Antibody - IHC of paraffin-embedded human kidney tissue using PP32 mouse mAb with DAB staining.
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Mouse Monoclonal [clone 8D2] (IgG1) to Human PHAP1 / ANP32A
Human
ELISA, IHC, IHC-P, WB
Unconjugated
100µl   $315.00
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
60µl   1mg/ml   $235.00; 120µl   1mg/ml   $295.00; 200µl   1mg/ml   $395.00
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Mouse Monoclonal (IgG1) to Human PHAP1 / ANP32A
Human
ELISA, IHC, WB
Unconjugated
50µl   1mg/ml   $315.00; 100µl   1mg/ml   $375.00; 200µl   1mg/ml   $435.00
PHAP1 / ANP32A Antibody - Western blot of recombinant PHAP1 / ANP32A.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal to Human PHAP1 / ANP32A
Rat, Human
ICC, IP, WB
Unconjugated
20µl   0.5mg/ml   $205.00; 100µl   0.5mg/ml   $255.00; 200µl   0.5mg/ml   $305.00; 1ml   0.5mg/ml   $530.00
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Human
IF, IHC, IHC-P
Unconjugated
50µl   $495.00
PHAP1 / ANP32A Antibody - Immunohistochemistry of paraffin-embedded human kidney using antibody at 1:100 dilution.
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Human
ELISA, IHC, IHC-P
Unconjugated
50µl   $285.00; 100µl   $385.00
PHAP1 / ANP32A Antibody - Immunohistochemistry (IHC) analysis of paraffin-embedded Human Kidney tissue with DAB staining using ANP32A Monoclonal Antibody.
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Mouse Monoclonal (IgG1) to Human PHAP1 / ANP32A
Human
ELISA, IHC, WB
Unconjugated
100µl   $345.00
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Human
ELISA, IHC, WB
Unconjugated
200µl   $590.00
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Human
ELISA, IHC, WB
PE Conjugated
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200µl   $740.00
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Human
ELISA, IHC, WB
AP Conjugated
200µl   $740.00
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Mouse Monoclonal (IgG1) to Human PHAP1 / ANP32A
Human
ICC, IP, WB
Unconjugated
100µg   $365.00
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Mouse Monoclonal [clone GF1] (IgG1) to Human PHAP1 / ANP32A
Human
ELISA, IHC
Unconjugated
100µl   $465.00
PHAP1 / ANP32A Antibody - ANP32A Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human tonsil tissue followed by peroxidase-conjugated secondary antibody and DAB staining.
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Rabbit Polyclonal to Human PHAP1 / ANP32A
Human
IHC, IHC-P, WB
Unconjugated
400µl   $325.00
PHAP1 / ANP32A Antibody - ANP32A antibody ARP40204_T100-NP_006296-ANP32A (acidic (leucine-rich) nuclear phosphoprotein 32 family, member A) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human heart.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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Rabbit Polyclonal (IgG) to Human PHAP1 / ANP32A
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100µl   0.5mg/ml   $335.00
PHAP1 / ANP32A Antibody - Immunohistochemical analysis of PHAP1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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Rabbit Polyclonal to Human PHAP1 / ANP32A
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50µl   1mg/ml   $255.00; 100µl   1mg/ml   $295.00; 200µl   1mg/ml   $375.00

Viewing 1-25 of 59 items


If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).