PHAP1 / ANP32A

acidic (leucine-rich) nuclear phosphoprotein 32 family, member A

Apoptosis is related to many diseases and development. Caspase-9 plays a central role in cell death induced by a variety of apoptosis activators. Cytochrome c, after released from mitochondria, binds to Apaf-1, which forms an apoptosome that in turn binds to and activate procaspase-9. Activated caspase-9 cleaves and activates the effector caspases (caspase-3, -6 and -7), which are responsible for the proteolytic cleavage of many key proteins in apoptosis. The tumor suppressor putative HLA-DR-associated proteins (PHAPs) were recently identified as important regulators of mitochondrion apoptosis. PHAP appears to facilitate apoptosome-medicated caspase-9 activation and to stimulate the mitochondrial apoptotic pathway. PHAP was also shown to oppose both Ras- and Myc-medicated cell transformation.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

PHAP1 / ANP32A (8)

Publications

No (8)

Tag

GST (1)

His (2)

His-GST (2)

Myc-DDK (Flag) (3)

Species

Human (6)

Mouse (1)

Source

293T Cells (1)

E. coli (4)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (3)

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Human PHAP1 / ANP32A Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66633

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.4 kDa

Price:

20 µg/$1,107

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Human PHAP1 / ANP32A Protein (Recombinant His-GST) (Glu2-Lys238) - LS-G97157

Source:

E. coli

Tag:

His-GST

Molecular Weight:

55.4 kDa

Price:

100 µg/$721

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Human PHAP1 / ANP32A Protein (Recombinant His) (aa2-249) - LS-G16029

Source:

E. coli

Tag:

His

Molecular Weight:

29.7 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Mouse PHAP1 / ANP32A Protein (Recombinant His-GST) (aa2-247) - LS-G16030

Source:

E. coli

Tag:

His-GST

Molecular Weight:

55.2 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human PHAP1 / ANP32A Protein (Recombinant GST) (Full Length) - LS-G31071

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

53.13 kDa

Price:

10 µg/$479; 25 µg/$670

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PHAP1 / ANP32A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115410

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.4 kDa

Price:

100 µg/$494

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Human PHAP1 / ANP32A Protein (Recombinant His) - LS-G938

Source:

E. coli

Tag:

His

Price:

50 µg/$411; 250 µg/$985; 10 µg/$276

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Human PHAP1 / ANP32A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78145

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

28.4 kDa

Price:

20 µg/$150

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