PHACTR4

Phosphatase And Actin Regulator 4

Regulator of protein phosphatase 1 (PP1) required for neural tube and optic fissure closure, and enteric neural crest cell (ENCCs) migration during development. Acts as an activator of PP1 by interacting with PPP1CA and preventing phosphorylation of PPP1CA at 'Thr-320'. During neural tube closure, localizes to the ventral neural tube and activates PP1, leading to down-regulate cell proliferation within cranial neural tissue and the neural retina. Also acts as a regulator of migration of enteric neural crest cells (ENCCs) by activating PP1, leading to dephosphorylation and subsequent activation of cofilin (COF1 or COF2) and repression of the integrin signaling through the RHO/ROCK pathway.

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Proteins (5)

Type

Over-Expression Lysate (4)

Recombinant (1)

Target

PHACTR4 (5)

Publications

No (5)

Tag

GST (1)

Myc-DDK (Flag) (4)

Species

Human (3)

Source

293T Cells (2)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PHACTR4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88572

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78 kDa

Price:

20 µg/$150

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Human PHACTR4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88574

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.9 kDa

Price:

20 µg/$150

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Human PHACTR4 Protein (Recombinant GST) (Full Length) - LS-G35099

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

95.6 kDa

Price:

2 µg/$439

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PHACTR4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110138

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78.9 kDa

Price:

100 µg/$494

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PHACTR4 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G119386

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

78 kDa

Price:

100 µg/$494

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