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PGIS / PTGIS

prostaglandin I2 (prostacyclin) synthase

PGIS / PTGIS is a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. However, this protein is considered a member of the cytochrome P450 superfamily on the basis of sequence similarity rather than functional similarity. This endoplasmic reticulum membrane protein catalyzes the conversion of prostglandin H2 to prostacyclin (prostaglandin I2), a potent vasodilator and inhibitor of platelet aggregation. An imbalance of prostacyclin and its physiological antagonist thromboxane A2 contribute to the development of myocardial infarction, stroke, and atherosclerosis.

Gene Name: prostaglandin I2 (prostacyclin) synthase
Synonyms: PTGIS, CYP8A1, Prostaglandin I2 synthase, Prostacyclin synthase, PTGI, CYP8, PGIS
Target Sequences: NM_000961 NP_000952.1 Q16647

☰ Filters
Antibodies (27)
ELISA Kits (11)
Proteins (6)
Competitive EIA (1)
Over-Expression Lysate (2)
Primary (27)
Recombinant (4)
Sandwich (9)
Sandwich CLIA (1)
PGIS / PTGIS (44)
Human (31)
Mouse (11)
Rat (18)
Bat (5)
Bovine (7)
Chicken (1)
Dog (5)
Gibbon (3)
Guinea pig (4)
Hamster (5)
Horse (2)
Monkey (6)
Pig (3)
Porcine (1)
Rabbit (2)
Sheep (2)
IHC (7)
IHC-P (6)
WB (22)
ELISA (4)
IF (1)
IP (1)
Peptide-ELISA (2)
rabbit (24)
mouse (2)
goat (1)
Product Group
IHCPlus (3)
IgG (10)
IgG1 (1)
IgG1,k (1)
monoclonal mc (2)
polyclonal pc (25)
3B11 (1)
isn-1 (1)
12 x 8-Well Microstrips (1)
96-Well Microplate (1)
96-Well Strip Plate (9)
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
FITC Conjugated (3)
HRP Conjugated (3)
PE Conjugated (1)
Unconjugated (14)
aa1-500 (8)
aa396-445 (4)
aa475-490 (2)
C-terminal (1)
aa248-258 (1)
aa299-329 (1)
aa30-61 (1)
aa472-500 (1)
No (44)
Cell Lysates (1)
Plasma (5)
Serum (5)
Tissue Homogenates (3)
GST (1)
GST, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (5)
293T Cells (1)
E. coli (1)
HEK 293 Cells (2)
Wheat Germ Extract (2)
Purified (1)
PGIS / PTGIS Antibody - Anti-PTGIS antibody IHC of human heart. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
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PGIS / PTGIS Rabbit anti-Mouse Polyclonal (aa475-490) Antibody
Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
1 Each/$485
PGIS / PTGIS Antibody - Anti-PTGIS antibody IHC of human lung, vessel. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PGIS / PTGIS Rabbit anti-Mouse Polyclonal (aa475-490) Antibody
Mouse, Dog, Bovine, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
1 Each/$665
PGIS / PTGIS Antibody - Western blot of PGIS / PTGIS antibody.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa1-500) Antibody
Mouse, Rat, Pig, Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
PGIS / PTGIS Antibody - Western blot of PGIS / PTGIS antibody.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa1-500) (HRP) Antibody
Rat, Human
WB
HRP Conjugated
100 µl/$325; 200 µl/$375; 500 µl/$539; 1 ml/$632; 2 ml/$867; 5 ml/$1,439
PGIS / PTGIS Antibody - Western blot of PGIS / PTGIS antibody.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa1-500) (Biotin) Antibody
Rat, Human
WB
Biotin Conjugated
100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217
PGIS / PTGIS Antibody - Western blot of PGIS / PTGIS antibody.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa1-500) (FITC) Antibody
Rat, Human
WB
FITC Conjugated
100 µl/$334; 200 µl/$387; 500 µl/$565; 1 ml/$682; 2 ml/$919; 5 ml/$1,549
PGIS / PTGIS Antibody - Western blot of PGIS / PTGIS antibody.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa1-500) (APC, Cy7) Antibody
Rat, Human
WB
APC, Cy7 Conjugated
100 µl/$476; 200 µl/$590; 500 µl/$1,069; 1 ml/$1,265; 2 ml/$1,771; 5 ml/$3,319
PGIS / PTGIS Antibody - Western blot of PGIS / PTGIS antibody.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa1-500) (Cy3) Antibody
Rat, Human
WB
Cy3 Conjugated
100 µl/$387; 200 µl/$463; 500 µl/$778; 1 ml/$933; 2 ml/$1,194; 5 ml/$2,213
PGIS / PTGIS Antibody - Western blot of PGIS / PTGIS antibody.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa1-500) (APC) Antibody
Rat, Human
WB
APC Conjugated
100 µl/$387; 200 µl/$463; 500 µl/$778; 1 ml/$933; 2 ml/$1,194; 5 ml/$2,213
PGIS / PTGIS Antibody - Western blot of PGIS / PTGIS antibody.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa1-500) (PE) Antibody
Rat, Human
WB
PE Conjugated
100 µl/$387; 200 µl/$463; 500 µl/$778; 1 ml/$933; 2 ml/$1,194; 5 ml/$2,213
PGIS / PTGIS Antibody - Anti-PTGIS antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PGIS / PTGIS Rabbit anti-Bovine Polyclonal (aa299-329) Antibody
Bovine, Human
IHC, IHC-P, WB
Unconjugated
1 Each/$485
PGIS / PTGIS Antibody - Formalin-fixed and paraffin-embedded human prostate carcinoma reacted with CYP8A1 Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa472-500) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PGIS / PTGIS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$764
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PGIS / PTGIS Mouse anti-Bovine Monoclonal (isn-1) Antibody
Rabbit, Mouse, Guinea pig, Sheep, Bovine, Rat
IHC, IP
Unconjugated
1 Each/$431
PGIS / PTGIS Antibody - Immunohistochemistry image of paraffin-embedded human melanoma cancer at a dilution of 1:100
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PGIS / PTGIS Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$294; 100 µg/$360
PGIS / PTGIS Antibody - Staining K562 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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PGIS / PTGIS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PGIS / PTGIS Antibody - Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with CYP8A1 antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa30-61) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PGIS / PTGIS Antibody - Western Blot analysis of PTGIS expression in transfected 293T cell line by PTGIS monoclonal antibody (M02), clone 3B11.Lane 1: PTGIS transfected lysate (Predicted MW: 57.1 KDa).Lane 2: Non-transfected lysate.
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PGIS / PTGIS Mouse anti-Human Monoclonal (3B11) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
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PGIS / PTGIS Rabbit anti-Human Polyclonal (C-terminal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PGIS / PTGIS Antibody - Western blot analysis of extracts from K562 cells, using PTGIS antibody.
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PGIS / PTGIS Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
PGIS / PTGIS Antibody - Antibody (0.5µg/ml) staining of Human Lung (A) and Ovary (B) lysates (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
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PGIS / PTGIS Goat anti-Human Polyclonal (aa248-258) Antibody
Human
Peptide-ELISA, WB
Unconjugated
100 µg/$503
PGIS / PTGIS Antibody - PTGIS antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa396-445) Antibody
Human
WB
Unconjugated
100 µl/$424
PGIS / PTGIS Antibody - PTGIS antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa396-445) (HRP) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Bat, Gibbon, Human, Monkey
WB
HRP Conjugated
100 µl/$469
PGIS / PTGIS Antibody - PTGIS antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PGIS / PTGIS Rabbit anti-Human Polyclonal (aa396-445) (Biotin) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Bat, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
PGIS / PTGIS Antibody - PTGIS antibody Western blot of Fetal Brain lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
Select
PGIS / PTGIS Rabbit anti-Human Polyclonal (aa396-445) (FITC) Antibody
Mouse, Dog, Guinea pig, Bovine, Rat, Hamster, Bat, Gibbon, Human, Monkey
WB
FITC Conjugated
100 µl/$469
Viewing 1-25 of 44 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).