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PFKP

phosphofructokinase, platelet

The PFKP gene encodes the platelet isoform of phosphofructokinase (PFK) (ATP:D-fructose-6-phosphate-1-phosphotransferase, EC 2.7.1.11). PFK catalyzes the irreversible conversion of fructose-6-phosphate to fructose-1,6-bisphosphate and is a key regulatory enzyme in glycolysis. The PFKP gene, which maps to chromosome 10p, is also expressed in fibroblasts. See also the muscle (PFKM; MIM 610681) and liver (PFKL; MIM 171860) isoforms of phosphofructokinase, which map to chromosomes 12q13 and 21q22, respectively. Vora (1981) [PubMed 6451249] determined that full tetrameric phophofructokinase enzyme expressed in platelets can be composed of subunits P4, P3L, and P2L2.

Gene Name: phosphofructokinase, platelet
Synonyms: PFKP, 6-phosphofructokinase type C, 6-phosphofructokinase, type c, PFK-C, PFKF, Phosphofructokinase 1, Phosphofructokinase, platelet, Phosphohexokinase
Target Sequences: NM_002627 NP_002618.1 Q01813

Publications (2)

1
A novel function of sphingosine kinase 1 suppression of JNK activity in preventing inflammation and injury. Di A, Kawamura T, Gao XP, Tang H, Berdyshev E, Vogel SM, Zhao YY, Sharma T, Bachmaier K, Xu J, Malik AB. The Journal of biological chemistry. 2010 285:15848-57. [PubMed:20299461] [PMC:PMC2871452] Related Antibodies: LS-B8456.
2
ZBTB7A acts as a tumor suppressor through the transcriptional repression of glycolysis. Xue-Song Liu, Jenna E Haines, Elie K Mehanna, Matthew D Genet, Issam Ben-Sahra, John M Asara, Brendan D Manning, Zhi-Min Yuan. Genes & development. 2014 September;28:1917-28. [PubMed:25184678] [PMC:PMC4197949] Related Antibodies: LS-C173559.

☰ Filters
Products
Antibodies (72)
Primary (72)
PFKP (72)
Human (72)
Mouse (23)
Rat (20)
African green monkey (1)
Gibbon (3)
Monkey (8)
Pig (8)
IHC (35)
IHC-P (13)
WB (70)
Flo (20)
ELISA (12)
ICC (2)
IF (17)
IP (4)
Peptide-ELISA (2)
rabbit (51)
mouse (21)
Product Group
IHCPlus (2)
IgG (19)
IgG1 (20)
IgG1,k (1)
monoclonal mc (21)
polyclonal pc (51)
1040CT4.6.4.4 (1)
OTI1A11 (2)
OTI1D6 (2)
OTI1F2 (2)
OTI2E10 (2)
OTI2E8 (2)
OTI2F2 (2)
OTI3A12 (2)
OTI3G8 (2)
OTI3H8 (2)
OTI5F7 (2)
APC (3)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (5)
Carrier-free (10)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (5)
HRP Conjugated (5)
PE Conjugated (4)
Unconjugated (43)
aa247-473 (8)
aa354-570 (8)
aa553-753 (8)
aa754-784 (7)
aa695-744 (4)
310-390 aa, Internal (1)
C-Terminus (1)
Gln365 (1)
Internal (1)
N-Terminus (1)
aa1-50 (1)
aa341-390 (1)
aa350-400 (1)
aa375-425 (1)
No (70)
Yes (2)
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PFKP mouse monoclonal antibody.
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PFKP Mouse anti-Human Monoclonal (OTI1D6) Antibody
Mouse, Rat, Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$450
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PFKP mouse monoclonal antibody.
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PFKP Mouse anti-Human Monoclonal (Carrier-free) (OTI1D6) Antibody
Mouse, Rat, Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PFKP Antibody - Anti-PFKP antibody IHC of human kidney, tubules. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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PFKP Rabbit anti-Human Polyclonal (aa754-784) Antibody
Human
IHC, IHC-P, WB
Unconjugated
200 µl/$440
PFKP Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-PFKP mouse monoclonal antibody.
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PFKP Mouse anti-Human Monoclonal (OTI3A12) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PFKP Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (Carrier-free) (OTI3A12) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PFKP Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (OTI3G8) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PFKP Antibody - IHC of paraffin-embedded Human Kidney tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (Carrier-free) (OTI3G8) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (OTI1A11) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (Carrier-free) (OTI1A11) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PFKP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
PFKP Mouse anti-Human Monoclonal (OTI2E8) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PFKP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
PFKP Mouse anti-Human Monoclonal (Carrier-free) (OTI2E8) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PFKP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
PFKP Mouse anti-Human Monoclonal (OTI1F2) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PFKP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
PFKP Mouse anti-Human Monoclonal (Carrier-free) (OTI1F2) Antibody
Human
Flo, IF, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (OTI2E10) Antibody
Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (Carrier-free) (OTI2E10) Antibody
Human, Monkey
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (OTI5F7) Antibody
Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human colon tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (Carrier-free) (OTI5F7) Antibody
Human, Monkey
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (OTI2F2) Antibody
Human, Monkey
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PFKP Antibody - IHC of paraffin-embedded Adenocarcinoma of Human breast tissue using anti-PFKP mouse monoclonal antibody.
Select
PFKP Mouse anti-Human Monoclonal (Carrier-free) (OTI2F2) Antibody
Human, Monkey
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PFKP Antibody - IHC of paraffin-embedded Human pancreas tissue using anti-PFKP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
PFKP Mouse anti-Human Monoclonal (OTI3H8) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
100 µl/$434
PFKP Antibody - IHC of paraffin-embedded Human pancreas tissue using anti-PFKP mouse monoclonal antibody. (Heat-induced epitope retrieval by 10mM citric buffer, pH6.0, 100C for 10min).
Select
PFKP Mouse anti-Human Monoclonal (Carrier-free) (OTI3H8) Antibody
Human
Flo, IHC, WB
Unconjugated, Carrier-free
100 µg/$511
PFKP Antibody - Immunohistochemical analysis of PFKP staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
PFKP Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human, Monkey
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
Select
PFKP Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$331
PFKP Antibody - Western blot of PFK-C antibody
Select
PFKP Rabbit anti-Human Polyclonal (310-390 aa, Internal) Antibody
Mouse, Rat, Human, Monkey
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PFKP Antibody - Anti-PFKM / PFK-1 antibody IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:67.
Select
PFKP Rabbit anti-Human Polyclonal (aa350-400) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).