PFKFB1

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1

PFKFB1 is a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

PFKFB1 (8)

Publications

No (8)

Tag

6His, C-terminus (2)

GST (1)

GST, N-terminus (1)

His, N-Terminal (1)

Myc-DDK (Flag) (3)

Species

Human (7)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (2)

Human Cells (1)

Mammalian Cells (1)

Wheat Germ Extract (2)

Purification

Purified (1)

Low Endotoxin Level

Low endotoxin level (2)

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Human PFKFB1 Protein (Recombinant GST, N-terminus) (aa1-100) - LS-G59572

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PFKFB1 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G64774

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.5 kDa

Price:

20 µg/$1,107

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Human PFKFB1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G74162

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.5 kDa

Price:

20 µg/$215

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Human PFKFB1 Protein (Recombinant GST) (Full Length) - LS-G29697

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

81.1 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PFKFB1 Protein (Recombinant 6His, C-terminus) (Ser2-Tyr471) - LS-G39910

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

55.6kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353

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Human PFKFB1 Protein (Recombinant His, N-Terminal) - LS-G144356

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

54.5 kDa

Price:

50 µg/$419

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Human PFKFB1 Protein (Recombinant 6His, C-terminus) (Ser2-Tyr471) - LS-G140164

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

55.6 kDa

Price:

10 µg/$344; 50 µg/$584

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PFKFB1 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G117855

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

54.5 kDa

Price:

100 µg/$710

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