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PFDN5 / MM1
prefoldin subunit 5
PFDN5 / MM1 is a member of the prefoldin alpha subunit family. The encoded protein is one of six subunits of prefoldin, a molecular chaperone complex that binds and stabilizes newly synthesized polypeptides, thereby allowing them to fold correctly. The complex, consisting of two alpha and four beta subunits, forms a double beta barrel assembly with six protruding coiled-coils. The encoded protein may also repress the transcriptional activity of the proto-oncogene c-Myc. Alternatively spliced transcript variants encoding different isoforms have been described.
| Gene Name: | prefoldin subunit 5 |
| Synonyms: | PFDN5, C-Myc-binding protein Mm-1, C-myc binding protein, MM-1, Myc modulator 1, Myc modulator-1, Prefoldin 5, MM1, PFD5, Prefoldin subunit 5 |
| Target Sequences: | NM_002624 NP_002615.2 Q99471 |
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