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PER2

period circadian clock 2

PER2 /Period circadian clock 2 is a member of the Period family of genes and is expressed in a circadian pattern in the suprachiasmatic nucleus, the primary circadian pacemaker in the mammalian brain. Genes in this family encode components of the circadian rhythms of locomotor activity, metabolism, and behavior. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene may increase the risk of getting certain cancers and have been linked to sleep disorders.

Gene Name: period circadian clock 2
Synonyms: PER2, HPER2, Period homolog 2 (Drosophila), Period 2, KIAA0347, Period (Drosophila) homolog 2, Period circadian clock 2, Period circadian protein 2, FASPS
Target Sequences: NM_022817 NP_073728.1 O15055

Publications (3)

1
Expression of clock proteins in developing tooth. Zheng L, Papagerakis S, Schnell SD, Hoogerwerf WA, Papagerakis P. Gene expression patterns : GEP. 11:202-6. (IHC; Mouse) [Full Text Article] [PubMed:21156215] [PMC:PMC3073654]
2
Calcium Sets the Clock in Ameloblasts. Raed Said, Liubov Lobanova, Silvana Papagerakis, Petros Papagerakis. Frontiers in physiology. 2020 August;11:920. [Full Text Article] [PubMed:32848861] [PMC:PMC7411184] Related Antibodies: LS-C2836.
3
Circadian rhythms regulate amelogenesis. Zheng L, Seon YJ, Mour[Character e3]o MA, Schnell S, Kim D, Harada H, Papagerakis S, Papagerakis P. Bone. 2014 Jul;55:158-65. [Full Text Article] [PubMed:23486183] [PMC:PMC3650122] Related Antibodies: LS-C2836.

☰ Filters
Antibodies (40)
ELISA Kits (2)
Proteins (2)
Primary (40)
Recombinant (2)
Sandwich (2)
PER2 (44)
Human (32)
Mouse (16)
Rat (14)
Horse (3)
IHC (13)
IHC-Fr (1)
IHC-P (4)
WB (36)
ELISA (8)
IF (5)
IP (1)
Peptide-ELISA (3)
rabbit (39)
mouse (1)
Product Group
IHCPlus (2)
IgG (19)
IgG2b,k (1)
monoclonal mc (1)
polyclonal pc (39)
5C10 (1)
96-Well Strip Plate (2)
APC (1)
APC Conjugated (1)
Biotin Conjugated (3)
Cy3 Conjugated (1)
Cy7 Conjugated (1)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
PE Conjugated (1)
Unconjugated (26)
aa179-436 (8)
C-Terminus (6)
pSer662 (3)
610-690 aa (2)
Ab-662 (1)
Ser662 (1)
aa1-50 (1)
aa13-330 (1)
aa636-685 (1)
No (43)
Yes (1)
Plasma (1)
Serum (1)
Tissue Homogenates (2)
GST, N-terminus (1)
His-S (1)
Human (1)
Rat (1)
E. coli (1)
Wheat Germ Extract (1)
Select
PER2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, WB
Unconjugated
0.1 ml/$386
Select
PER2 Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, IF, IHC, IHC-Fr, WB
Unconjugated
100 µg/$832
PER2 Antibody - PER2 Antibody western blot of human samples
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PER2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
WB
Unconjugated
25 µg/$364; 100 µg/$511
PER2 Antibody - Western blot of Phospho-Per2 (S662) antibody
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PER2 Rabbit anti-Human Polyclonal (610-690 aa) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PER2 Antibody - Anti-PER2 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PER2 Mouse anti-Human Monoclonal (5C10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
PER2 Antibody - PER2 antibody Western blot of Placenta lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PER2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
WB
Unconjugated
100 µl/$424
PER2 Antibody - Human Skeletal Muscle: Formalin-Fixed, Paraffin-Embedded (FFPE)
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PER2 Rabbit anti-Human Polyclonal (aa636-685) Antibody
Mouse, Human
IF, IHC, IHC-P, Peptide-ELISA
Unconjugated
100 µl/$515
PER2 Antibody - Immunohistochemical analysis of PER2 (pS662) staining in human prostate cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
Select
PER2 Rabbit anti-Human Polyclonal (pSer662) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$341
PER2 Antibody - 1:100 staining mouse lung tissue by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
Select
PER2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Select
PER2 Rabbit anti-Human Polyclonal (610-690 aa) Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PER2 Antibody - Peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using Period Circadian Protein 2 antibody.
Select
PER2 Rabbit anti-Human Polyclonal (Ab-662) Antibody
Mouse, Human
ELISA, IF, IHC
Unconjugated
100 µg/$357
PER2 Antibody - Immunohistochemistry analysis of paraffin-embedded human brain, using Period Circadian Protein 2 (Phospho-Ser662) Antibody. The picture on the right is blocked with the phospho peptide.
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PER2 Rabbit anti-Human Polyclonal (pSer662) Antibody
Mouse, Human
IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PER2 Antibody - P-peptide - + Immunohistochemistry analysis of paraffin-embedded human brain tissue using Period Circadian Protein 2 (Phospho-Ser662) antibody.
Select
PER2 Rabbit anti-Human Polyclonal (pSer662) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
Select
PER2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$351
PER2 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using PER2 Polyclonal Antibody at dilution of 1:50.
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PER2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
PER2 Antibody - Western blot blot of extracts of various cells, using Per2 antibody.
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PER2 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
Select
PER2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µl/$649
Select
PER2 Rabbit anti-Human Polyclonal (Ser662) Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$357
Select
PER2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$357
PER2 Antibody - Detection of Human Per2 by Western Blot. Samples: Whole cell lysate from K562 (5, 15 and 50 ug) and MCF7 (M; 50 ug) cells. Antibodies: Affinity purified rabbit anti-Per2 antibody used for WB at 0.4 ug/ml. Detection: Chemiluminescence with an exposure time of 3 minutes.
Select
PER2 Rabbit anti-Human Polyclonal (aa1-50) Antibody
Human
WB
Unconjugated
100 µl/$448
PER2 Antibody - Western blot analysis of extracts of mouse liver, using PER2 antibody at 1:3000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
PER2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PER2 Antibody - Western blot analysis of extracts of various cell lines, using PER2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
Select
PER2 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
20 µl/$275; 50 µl/$311; 100 µl/$389; 200 µl/$503
PER2 Antibody - PER2 antibody Western blot. All lanes: Anti PER2 at 0.5 ug/ml. Lane 1: A549 Whole Cell Lysate at 40 ug. Lane 2: PANC Whole Cell Lysate at 40 ug. Predicted band size: 136 kD. Observed band size: 136 kD.
Select
PER2 Rabbit anti-Human Polyclonal (aa13-330) Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
PER2 Antibody - Western blot analysis of extracts of mouse liver using PER2 Polyclonal Antibody at dilution of 1:3000.
Select
PER2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
PER2 Antibody - Western blot testing of PER2 antibody and Lane 1: A549; 2: PANC lysate
Select
PER2 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
100 µg/$575
Viewing 1-25 of 44 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).