PELI2 / Pellino 2

pellino E3 ubiquitin protein ligase family member 2

E3 ubiquitin ligase catalyzing the covalent attachment of ubiquitin moieties onto substrate proteins. Involved in the TLR and IL-1 signaling pathways via interaction with the complex containing IRAK kinases and TRAF6. Mediates IL1B-induced IRAK1 'Lys-63'-linked polyubiquitination and possibly 'Lys-48'-linked ubiquitination. May be important for LPS- and IL1B-induced MAP3K7-dependent, but not MAP3K3-dependent, NF-kappa-B activation. Can activate the MAP (mitogen activated protein) kinase pathway leading to activation of ELK1.

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Products

Proteins (4)

Type

Over-Expression Lysate (2)

Recombinant (2)

Target

PELI2 / Pellino 2 (4)

Publications

No (4)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (2)

Species

Human (3)

Source

293T Cells (1)

E. coli (1)

HEK 293 Cells (1)

Wheat Germ Extract (1)

Purification

Purified (2)

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PELI2 / Pellino 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G110648

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.3 kDa

Price:

100 µg/$494

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Human PELI2 / Pellino 2 Protein (Recombinant His) - LS-G3009

Source:

E. coli

Tag:

His

Price:

50 µg/$361; 250 µg/$739; 10 µg/$261

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Human PELI2 / Pellino 2 Protein (Recombinant GST) (Full Length) - LS-G34679

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

72.8 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PELI2 / Pellino 2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G83502

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.3 kDa

Price:

20 µg/$150

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