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PEG1 / MEST
mesoderm specific transcript
PEG1 / MEST encodes a member of the alpha/beta hydrolase superfamily. It is imprinted, exhibiting preferential expression from the paternal allele in fetal tissues, and isoform-specific imprinting in lymphocytes. The loss of imprinting of this gene has been linked to certain types of cancer and may be due to promotor switching. The encoded protein may play a role in development. Alternatively spliced transcript variants encoding multiple isoforms have been identified for this gene. Pseudogenes of this gene are located on the short arm of chromosomes 3 and 4, and the long arm of chromosomes 6 and 15.
| Gene Name: | mesoderm specific transcript |
| Synonyms: | MEST, Mesoderm specific transcript, PEG1 |
| Target Sequences: | NM_002402 NP_002393.2 Q5EB52 |
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