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PEG / Polyethylene Glycol
When attached to various protein medications, polyethylene glycol allows a slowed clearance of the carried protein from the blood. This makes for a longer-acting medicinal effect and reduces toxicity, and it allows longer dosing intervals. Examples include PEG-interferon alpha, which is used to treat hepatitis C, and PEGfilgrastim (Neulasta), which is used to treat neutropenia. It has been shown that polyethylene glycol can improve healing of spinal injuries in dogs. One of the earlier findings, that polyethylene glycol can aid in nerve repair, came from the University of Texas (Krause and Bittner). Antibodies to PEG can be used to detect PEGylated proteins in various assays, including immunohistochemistry.
PEG / Polyethylene Glycol Target Details
| Target Name: | PEG / Polyethylene Glycol |
| Target Abbreviation: | PEG |
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