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Unfortunately, the antibody (ID:196072) is no longer available.

Below is a list of antibodies to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



PECAM-1 / CD31

platelet/endothelial cell adhesion molecule 1

Induces susceptibility to atherosclerosis (By similarity). Cell adhesion molecule which is required for leukocyte transendothelial migration (TEM) under most inflammatory conditions. Tyr-690 plays a critical role in TEM and is required for efficient trafficking of PECAM1 to and from the lateral border recycling compartment (LBRC) and is also essential for the LBRC membrane to be targeted around migrating leukocytes. Prevents phagocyte ingestion of closely apposed viable cells by transmitting 'detachment' signals, and changes function on apoptosis, promoting tethering of dying cells to phagocytes (the encounter of a viable cell with a phagocyte via the homophilic interaction of PECAM1 on both cell surfaces leads to the viable cell's active repulsion from the phagocyte. During apoptosis, the inside-out signaling of PECAM1 is somehow disabled so that the apoptotic cell does not actively reject the phagocyte anymore. The lack of this repulsion signal together with the interaction of the eat-me signals and their respective receptors causes the attachment of the apoptotic cell to the phagocyte, thus triggering the process of engulfment). Isoform Delta15 is unable to protect against apoptosis. Modulates BDKRB2 activation. Regulates bradykinin- and hyperosmotic shock-induced ERK1/2 activation in human umbilical cord vein cells (HUVEC).

Gene Name: platelet/endothelial cell adhesion molecule 1
Synonyms: PECAM1, CD31, CD31 antigen, EndoCAM, PECA1, PECAM-1, GPIIA
Target Sequences: NM_000442 NP_000433.4 P16284

Publications (13)

1
Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Rosenblum WI, Murata S, Nelson GH, Werner PK, Ranken R, Harmon RC. Development (Cambridge, England). 1994 120:2539-53. [PubMed:7956830]
2
Anti-CD31 delays platelet adhesion/aggregation at sites of endothelial injury in mouse cerebral arterioles. Rosenblum WI, Murata S, Nelson GH, Werner PK, Ranken R, Harmon RC. The American journal of pathology. 1994 145:33-6. [PubMed:8030753] [PMC:PMC1887306]
3
Monoclonal antibodies specific for endothelial cells of mouse blood vessels. Their application in the identification of adult and embryonic endothelium. DeLisser HM, Christofidou-Solomidou M, Strieter RM, Burdick MD, Robinson CS, Wexler RS, Kerr JS, Garlanda C, Merwin JR, Madri JA, Albelda SM. European journal of cell biology. 1994 63:247-54. [PubMed:8082649]
4
Neutrophil platelet endothelial cell adhesion molecule-1 participates in neutrophil recruitment at inflammatory sites and is down-regulated after leukocyte extravasation. Christofidou-Solomidou M, Nakada MT, Williams J, Muller WA, DeLisser HM. Journal of immunology (Baltimore, Md. : 1950). 1997 158:4872-8. [PubMed:9144503]
5
Involvement of endothelial PECAM-1/CD31 in angiogenesis. DeLisser HM, Christofidou-Solomidou M, Strieter RM, Burdick MD, Robinson CS, Wexler RS, Kerr JS, Garlanda C, Merwin JR, Madri JA, Albelda SM. The American journal of pathology. 1997 151:671-7. [PubMed:9284815] [PMC:PMC1857836]
6
Circulating vascular progenitor cells do not contribute to compensatory lung growth. Voswinckel R, Ziegelhoeffer T, Heil M, Kostin S, Breier G, Mehling T, Haberberger R, Clauss M, Gaumann A, Schaper W, Seeger W. Circulation research. 2003 93:372-9. [PubMed:12881479]
7
Endosialin (TEM1, CD248) is a marker of stromal fibroblasts and is not selectively expressed on tumour endothelium. MacFadyen JR, Haworth O, Roberston D, Hardie D, Webster MT, Morris HR, Panico M, Sutton-Smith M, Dell A, van der Geer P, Wienke D, Buckley CD, Isacke CM. FEBS letters. 2005 579:2569-75. [PubMed:15862292] Related Antibodies: LS-C40811.
8
Identification of functional endothelial progenitor cells suitable for the treatment of ischemic tissue using human umbilical cord blood. Nagano M, Yamashita T, Hamada H, Ohneda K, Kimura K, Nakagawa T, Shibuya M, Yoshikawa H, Ohneda O. Blood. 2007 110:151-60. [PubMed:17379743] Related Antibodies: LS-C40811.
9
Vascular pathology in dermatomyositis and anatomic relations to myopathology. Pestronk A, Schmidt RE, Choksi R. Muscle & nerve. 2010 42:53-61. (IHC; Human) [Full Text Article] [PubMed:20544925] Related Antibodies: LS-B3446.
10
Targeting tumor-associated endothelial cells: anti-VEGFR2 immunoliposomes mediate tumor vessel disruption and inhibit tumor growth. Wicki A, Rochlitz C, Orleth A, Ritschard R, Albrecht I, Herrmann R, Christofori G, Mamot C. Clinical cancer research : an official journal of the American Association for Cancer Research. 2012 18:454-64. [PubMed:22065082] Related Antibodies: LS-C40811.
11
Quercetin inhibits angiogenesis mediated human prostate tumor growth by targeting VEGFR- 2 regulated AKT/mTOR/P70S6K signaling pathways. Pratheeshkumar P, Budhraja A, Son YO, Wang X, Zhang Z, Ding S, Wang L, Hitron A, Lee JC, Xu M, Chen G, Luo J, Shi X. PloS one. 2012 7:e47516. (IHC; Human) [PubMed:23094058] [PMC:PMC3475699]
12
Luteolin inhibits human prostate tumor growth by suppressing vascular endothelial growth factor receptor 2-mediated angiogenesis. Pratheeshkumar P, Son YO, Budhraja A, Wang X, Ding S, Wang L, Hitron A, Lee JC, Kim D, Divya SP, Chen G, Zhang Z, Luo J, Shi X. PloS one. 2012 7:e52279. (IHC; Mouse) [PubMed:23300633] [PMC:PMC3534088]
13
Activation of the Wnt/planar cell polarity pathway is required for pericyte recruitment during pulmonary angiogenesis. Yuan K, Orcholski ME, Panaroni C, Shuffle EM, Huang NF, Jiang X, Tian W, Vladar EK, Wang L, Nicolls MR, Wu JY, de Jesus Perez VA. The American journal of pathology. Jan;185:69-84. [Full Text Article] [PubMed:25447046] [PMC:PMC4278244] Related Antibodies: LS-B4737.
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Filtered By: None
Target
pecam-1-cd31 (351)
Reactivity
Human (239)
Mouse (112)
Rat (57)
Baboon (1)
Bovine (8)
Cat (1)
Chicken (1)
Cynomolgus monkey (7)
Dog (3)
Donkey (1)
Gibbon (1)
Goat (8)
Guinea pig (1)
Hamster (5)
Horse (1)
Monkey (7)
Orangutan (1)
Pig (12)
Rabbit (14)
Rhesus monkey (3)
Sheep (8)
Application
IHC (79)
IHC-Fr (43)
IHC-P (87)
WB (164)
Flo (201)
Block (1)
ELISA (66)
Func (11)
ICC (18)
IF (86)
IP (58)
Host
rabbit (89)
mouse (206)
goat (4)
hamster (6)
hamster-armenian (1)
rat (45)
Isotype
IgG (73)
IgG1 (139)
IgG1,k (34)
IgG2a (26)
IgG2a,k (14)
IgG2b (1)
IgG2b,k (7)
IgM (2)
Clonality
monoclonal mc (263)
polyclonal pc (88)
Clone
11n31 (1)
158-2B3 (9)
1A10 (6)
1B10 (1)
1C2 (1)
1D2 (1)
1D2-1A5 (1)
1D4B (2)
1F9 (1)
1G6 (1)
1H4 (1)
1H6 (1)
2A4 (1)
2B5 (1)
2C3 (1)
2C6 (1)
2E4 (1)
2F4 (1)
2F7B2 (1)
2H8 (1)
390 (25)
3B5 (1)
3G4 (1)
3H2 (1)
3H3 (1)
4C1 (1)
4D1 (1)
5A9 (1)
8A9 (1)
B493 (1)
BC16-6.4EF (1)
BV8 (3)
C31.10 (3)
C31.12 (2)
C31.3 (3)
C31.3 + C31.7 + C31.10 (3)
C31.3 + JC/70A (3)
C31.7 (5)
CLB-HEC/75 (2)
CO.3E1D4 (2)
EP3095 (1)
ER-MP12 (3)
HC1/6 (3)
hCD31 (3)
HEC7 (1)
JC/70A (5)
LCI-4 (5)
MEC 7.46 (4)
MEC13.3 (5)
MEC7.46 (4)
MEM-05 (8)
PCM25-1 (3)
PECAM-1 (1)
Rabbit Monoclonal RMCD31-1 (2)
SP164 (1)
SP38 (1)
SPM532 (3)
TLD-3A12 (3)
VM64 (1)
WM59 (2)
WM-59 (WM59) (5)
Format
AP Conjugated (13)
APC Conjugated (17)
Azide-free (15)
Biotin Conjugated (37)
Cy7 Conjugated (4)
DY488 Conjugated (3)
DY550 Conjugated (3)
DY594 Conjugated (1)
DY650 Conjugated (2)
FITC Conjugated (38)
HRP Conjugated (16)
Low Endotoxin (2)
PE (4)
PE Conjugated (22)
PerCP Conjugated (2)
Ready-to-Use (9)
RPE (1)
RPE Conjugated (4)
Unconjugated (189)
Epitope
C-Terminus (6)
aa199-287 (6)
pTyr713 (6)
aa511-540 (5)
N-Terminus (3)
aa226-389 (3)
aa421-629 (3)
aa459-624 (3)
aa78-214 (3)
Extracellular Domain (2)
Internal (2)
aa18-590 (2)
Ala280 (1)
Thr709 (1)
aa100-300 (1)
aa231-280 (1)
aa28-382 (1)
aa508-536 (1)
aa547-566 (1)
aa660-709 (1)
aa660-740 (1)
aa686-735 (1)
aa690-718 (1)
aa717-732 (1)
aa730-734 (1)
Publications
No (348)
Yes (3)
Showing 1-25 out of 351 results
Anti-PECAM-1 / CD31 Antibody IHC-plus™ LS-B4737

Rabbit Polyclonal to Mouse PECAM-1 / CD31
Mouse, Human
IHC-P
Unconjugated
Anti-PECAM-1 / CD31 Antibody IHC-plus™ LS-B3446

Mouse Monoclonal (IgG1) to Human PECAM-1 / CD31
Human
ELISA IHC-P WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone 1H6) IHC-plus™ LS-B10502

Mouse Monoclonal [clone 1H6] (IgG1) to Human PECAM-1 / CD31
Dog, Human
Flo IF IHC-P WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (aa686-735) IHC-plus™ LS-B5577

Rabbit Polyclonal (IgG) to Human PECAM-1 / CD31
Mouse, Human
ELISA IF IHC-P WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone 2F7B2) IHC-plus™ LS-B2364

Mouse Monoclonal [clone 2F7B2] (IgG1) to Human PECAM-1 / CD31
Human
ELISA IHC-P WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone 2E4) LS-C173988

Mouse Monoclonal [clone 2E4] (IgG2b) to Human PECAM-1 / CD31
Human
Flo IF IHC-P WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone BC16-6.4EF) LS-C348736

Mouse Monoclonal [clone BC16-6.4EF] (IgG1) to Human PECAM-1 / CD31
Mouse, Rat, Human
Func ICC IF IHC-Fr IHC-P WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone TLD-3A12) LS-C43483

Mouse Monoclonal [clone TLD-3A12] (IgG1) to Rat PECAM-1 / CD31
Rat
ELISA Flo IHC-Fr WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (FITC) LS-C43480

Mouse Monoclonal (IgG1) to Rat PECAM-1 / CD31
Rat
ELISA Flo IHC-Fr WB
FITC Conjugated
Anti-PECAM-1 / CD31 Antibody (aa18-590) LS-C150165

Goat Polyclonal (IgG) to Mouse PECAM-1 / CD31
Mouse
Flo IHC WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone ER-MP12) LS-C96348

Rat Monoclonal [clone ER-MP12] (IgG2a)
Mouse
IHC-Fr IHC-P
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone CO.3E1D4, FITC) LS-C43279

Mouse Monoclonal [clone CO.3E1D4] (IgG2a) to Sheep PECAM-1 / CD31
Goat, Sheep, Bovine
Flo
FITC Conjugated
Anti-PECAM-1 / CD31 Antibody (clone LCI-4, APC) LS-C57471

Mouse Monoclonal [clone LCI-4] (IgG1) to Pig PECAM-1 / CD31
Pig, Human
Flo
APC Conjugated
Anti-PECAM-1 / CD31 Antibody (clone WM59) LS-C40811

Mouse Monoclonal [clone WM59] (IgG1) to Human PECAM-1 / CD31
Human, Monkey, Baboon
Flo IF IHC-Fr
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone TLD-3A12, Low Endotoxin) LS-C43479

Mouse Monoclonal [clone TLD-3A12] (IgG1) to Rat PECAM-1 / CD31
Rat
ELISA Flo IHC-Fr WB
Unconjugated, Low Endotoxin
Anti-PECAM-1 / CD31 Antibody (clone EP3095) IHC-plus™ LS-B11068

Rabbit Monoclonal [clone EP3095] (IgG) to Human PECAM-1 / CD31
Human
Flo IHC-P WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone ER-MP12, Biotin) LS-C96364

Rat Monoclonal [clone ER-MP12]
Mouse
IHC-Fr IHC-P
Biotin Conjugated
Anti-PECAM-1 / CD31 Antibody (clone MEC13.3) LS-C142316

Rat Monoclonal [clone MEC13.3] (IgG2a,k) to Mouse PECAM-1 / CD31
Mouse
Flo ICC IHC-Fr IHC-P IP
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone 1D2-1A5) IHC-plus™ LS-B5414

Mouse Monoclonal [clone 1D2-1A5] (IgG1,k) to Human PECAM-1 / CD31
Human
ELISA IHC-P IP WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone 390, FITC) LS-C4937

Rat Monoclonal [clone 390] (IgG2a,k) to Mouse PECAM-1 / CD31
Mouse
Flo Func IHC-Fr IP
FITC Conjugated
Anti-PECAM-1 / CD31 Antibody LS-C43872

Mouse Monoclonal (IgM) to Pig PECAM-1 / CD31
Pig
Flo IHC-Fr
Unconjugated
Anti-PECAM-1 / CD31 Antibody (Biotin) LS-C35538

Mouse Monoclonal (IgG1) to Human PECAM-1 / CD31
Human
Flo
Biotin Conjugated
Anti-PECAM-1 / CD31 Antibody (aa231-280) IHC-plus™ LS-B12093

Rabbit Polyclonal (IgG) to Human PECAM-1 / CD31
Mouse, Rat, Human
ELISA IHC-P WB
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone JC/70A) IHC-plus™ LS-B5167

Mouse Monoclonal [clone JC/70A] (IgG1,k) to Human PECAM-1 / CD31
Human
IF IHC-P
Unconjugated
Anti-PECAM-1 / CD31 Antibody (clone MEC7.46, Biotin) LS-C139850

Rat Monoclonal [clone MEC7.46] (IgG1) to Mouse PECAM-1 / CD31
Mouse
Flo IF IHC-Fr IP
Biotin Conjugated

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If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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