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PEBP1 / RKIP
phosphatidylethanolamine binding protein 1
Binds ATP, opioids and phosphatidylethanolamine. Has lower affinity for phosphatidylinositol and phosphatidylcholine. Serine protease inhibitor which inhibits thrombin, neuropsin and chymotrypsin but not trypsin, tissue type plasminogen activator and elastase By similarity. Inhibits the kinase activity of RAF1 by inhibiting its activation and by dissociating the RAF1/MEK complex and acting as a competitive inhibitor of MEK phosphorylation.
| Gene Name: | phosphatidylethanolamine binding protein 1 |
| Synonyms: | PEBP1, HCNP, HCNPpp, PBP, Prostatic binding protein, Raf kinase inhibitor protein, Raf kinase inhibitory protein, Prostatic-binding protein, Neuropolypeptide h3, PEBP, PEBP-1, RKIP |
| Target Sequences: | NM_002567 NP_002558.1 P30086 |
Publications (2)
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