PDK3

pyruvate dehydrogenase kinase, isozyme 3

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle, and thus is one of the major enzymes responsible for the regulation of glucose metabolism. The enzymatic activity of PDH is regulated by a phosphorylation/dephosphorylation cycle, and phosphorylation results in inactivation of PDH. The protein encoded by this gene is one of the three pyruvate dehydrogenase kinases that inhibits the PDH complex by phosphorylation of the E1 alpha subunit. This gene is predominantly expressed in the heart and skeletal muscles. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (9)

Type

Over-Expression Lysate (4)

Recombinant (5)

Target

PDK3 (9)

Publications

No (9)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

His (1)

Myc-DDK (Flag) (5)

Species

Human (5)

Mouse (2)

Source

293T Cells (2)

E. coli (2)

HEK 293 Cells (3)

Wheat Germ Extract (2)

Purification

Purified (2)

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PDK3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125898

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.9 kDa

Price:

100 µg/$494

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Mouse PDK3 Protein (Recombinant His) (aa138-396) - LS-G25304

Source:

E. coli

Tag:

His

Molecular Weight:

33.1 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human PDK3 Protein (Recombinant GST) (Full Length) - LS-G29674

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

73.3 kDa

Price:

2 µg/$439

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Mouse PDK3 Protein (Recombinant 6His, N-terminus) (aa131-362) - LS-G56879

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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Human PDK3 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G68015

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

20 µg/$1,107

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Human PDK3 Protein (Recombinant GST, N-terminus) (aa174-263) - LS-G59553

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PDK3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81241

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.9 kDa

Price:

20 µg/$150

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Human PDK3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G81242

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

20 µg/$150

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PDK3 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100538

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

46.8 kDa

Price:

100 µg/$494

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