PDHA1 / PDH E1 Alpha

pyruvate dehydrogenase (lipoamide) alpha 1

The pyruvate dehydrogenase (PDH) complex is a nuclear-encoded mitochondrial multienzyme complex that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2), and provides the primary link between glycolysis and the tricarboxylic acid (TCA) cycle. The PDH complex is composed of multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). The E1 enzyme is a heterotetramer of two alpha and two beta subunits. This gene encodes the E1 alpha 1 subunit containing the E1 active site, and plays a key role in the function of the PDH complex. Mutations in this gene are associated with pyruvate dehydrogenase E1-alpha deficiency and X-linked Leigh syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Products

Proteins (11)

Type

Over-Expression Lysate (8)

Recombinant (3)

Target

PDHA1 / PDH E1 Alpha (11)

Publications

No (11)

Tag

GST (1)

His (1)

Myc-DDK (Flag) (9)

Species

Human (7)

Source

293T Cells (4)

E. coli (1)

HEK 293 Cells (5)

Wheat Germ Extract (1)

Purification

Purified (1)

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Human PDHA1 / PDH E1 Alpha Protein (Recombinant His) (aa30-390) - LS-G12788

Source:

E. coli

Tag:

His

Molecular Weight:

41.7 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$707; 200 µg/$885; 1 mg/$1,994; 500 µg/$1,534; 5 mg/$3,095; 2 mg/$2,181

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Human PDHA1 / PDH E1 Alpha Protein (Recombinant GST) (Full Length) - LS-G29672

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

68.64 kDa

Price:

10 µg/$479; 25 µg/$670

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Human PDHA1 / PDH E1 Alpha Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66786

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.2 kDa

Price:

20 µg/$1,107

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PDHA1 / PDH E1 Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129733

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.6 kDa

Price:

100 µg/$494

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PDHA1 / PDH E1 Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129671

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.6 kDa

Price:

100 µg/$494

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PDHA1 / PDH E1 Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G129801

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48 kDa

Price:

100 µg/$494

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Human PDHA1 / PDH E1 Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78496

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.3 kDa

Price:

20 µg/$150

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Human PDHA1 / PDH E1 Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78497

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

48 kDa

Price:

20 µg/$150

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Human PDHA1 / PDH E1 Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78498

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

44.6 kDa

Price:

20 µg/$150

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Human PDHA1 / PDH E1 Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78499

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

40.6 kDa

Price:

20 µg/$150

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PDHA1 / PDH E1 Alpha Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98995

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

43.3 kDa

Price:

100 µg/$494

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