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Unfortunately, the ELISA kit (ID:1705) is no longer available.

Below is a list of ELISA kits to the same protein target. You may also try your search again using the search box at the top of the page. Please contact us if you have any questions.



PDGFRA / PDGFR Alpha

platelet-derived growth factor receptor, alpha polypeptide

Tyrosine-protein kinase that acts as a cell-surface receptor for PDGFA, PDGFB and PDGFC and plays an essential role in the regulation of embryonic development, cell proliferation, survival and chemotaxis. Depending on the context, promotes or inhibits cell proliferation and cell migration. Plays an important role in the differentiation of bone marrow-derived mesenchymal stem cells. Required for normal skeleton development and cephalic closure during embryonic development. Required for normal development of the mucosa lining the gastrointestinal tract, and for recruitment of mesenchymal cells and normal development of intestinal villi. Plays a role in cell migration and chemotaxis in wound healing. Plays a role in platelet activation, secretion of agonists from platelet granules, and in thrombin-induced platelet aggregation. Binding of its cognate ligands - homodimeric PDGFA, homodimeric PDGFB, heterodimers formed by PDGFA and PDGFB or homodimeric PDGFC -leads to the activation of several signaling cascades; the response depends on the nature of the bound ligand and is modulated by the formation of heterodimers between PDGFRA and PDGFRB. Phosphorylates PIK3R1, PLCG1, and PTPN11. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate, mobilization of cytosolic Ca2+ and the activation of protein kinase C. Phosphorylates PIK3R1, the regulatory subunit of phosphatidylinositol 3-kinase, and thereby mediates activation of the AKT1 signaling pathway. Mediates activation of HRAS and of the MAP kinases MAPK1/ERK2 and/or MAPK3/ERK1. Promotes activation of STAT family members STAT1, STAT3 and STAT5A and/or STAT5B. Receptor signaling is down-regulated by protein phosphatases that dephosphorylate the receptor and its down-stream effectors, and by rapid internalization of the activated receptor.

Gene Name: platelet-derived growth factor receptor, alpha polypeptide
Family/Subfamily: Protein Kinase , PDGF Receptor
Synonyms: PDGFRA, CD140A, CD140a antigen, PDGFalphaR, PDGFR2, PDGFRalpha, AlphaPDGFR, RHEPDGFRA, PDGF receptor alpha, PDGFR-2, PDGFRA/BCR fusion, APDGFR, Pdgf alpha-receptor, PDGF-R-alpha, PDGFR-alpha
Target Sequences: NM_006206 NP_006197.1 P16234

Filtered By: None
Target
pdgfra-pdgfr-alpha (170)
Reactivity
Human (149)
Mouse (85)
Rat (35)
Bat (2)
Bovine (4)
Chicken (2)
Dog (3)
Guinea pig (1)
Hamster (1)
Horse (3)
Monkey (3)
Pig (4)
Rabbit (1)
Sheep (2)
Xenopus (1)
Application
IHC (61)
IHC-Fr (1)
IHC-P (23)
WB (128)
Flo (18)
DB (7)
ELISA (90)
ICC (12)
IF (18)
IP (8)
Host
rabbit (132)
mouse (27)
rat (11)
Isotype
IgG (102)
IgG1 (16)
IgG1,k (1)
IgG2a (2)
IgG2a,k (11)
IgG2b (2)
Clonality
monoclonal mc (39)
polyclonal pc (131)
Clone
16A1 (4)
1A11 (1)
1H10 (1)
2B12 (1)
2D2-1A11 (1)
2E9 (1)
35248 (57/20) (1)
3F4 (1)
4E7 (1)
4G5 (1)
6E2 (1)
APA5 (4)
Format
AP Conjugated (12)
APC Conjugated (14)
Azide-free (7)
Biotin Conjugated (16)
CF Conjugated (1)
FITC Conjugated (14)
HRP Conjugated (13)
PE Conjugated (14)
Unconjugated (86)
Epitope
C-Terminus (12)
Tyr762 (9)
pTyr762 (9)
Tyr720 (8)
Tyr754 (8)
Tyr768 (8)
aa677-706 (7)
aa789-1089 (5)
pTyr754 (4)
pTyr849 (4)
aa170-387 (3)
aa32-324 (3)
aa1035-1053 (2)
pTyr742 (2)
Extracellular Domain (1)
Ile843 (1)
Ser1057 (1)
Tyr742 (1)
aa1010-1090 (1)
aa1030-1043 (1)
aa1031-1080 (1)
aa1048-1077 (1)
aa1063-1077 (1)
aa351-400 (1)
aa678-706 (1)
aa690-770 (1)
aa700-780 (1)
aa721-770 (1)
aa731-780 (1)
aa790-870 (1)
aa816-865 (1)
aa960-1040 (1)
aa968-1002 (1)
pTyr1018 (1)
Publications
No (169)
Yes (1)
Showing 1-25 out of 170 results
Anti-PDGFRA / PDGFR Alpha Antibody (aa1035-1053) IHC-plus™ LS-B6056

Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Xenopus, Chicken, Bovine, Rat, Hamster, Pig, Horse, Bat, Rabbit, Mouse, Dog, Human, Monkey
IHC-P IP WB
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (C-Terminus) IHC-plus™ LS-B2172

Rabbit Polyclonal to Human PDGFRA / PDGFR Alpha
Mouse, Rat, Human
IHC-P
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (aa1063-1077) IHC-plus™ LS-B857

Rabbit Polyclonal to Human PDGFRA / PDGFR Alpha
Human
ELISA IHC-P
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (clone APA5) LS-C106627

Rat Monoclonal [clone APA5] (IgG2a,k) to Mouse PDGFRA / PDGFR Alpha
Mouse
Flo IHC-Fr WB
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (Extracellular Domain, clone 35248 (57/20)) LS-C11204

Mouse Monoclonal [clone 35248 (57/20)] (IgG1) to Human PDGFRA / PDGFR Alpha
Human
ELISA IHC-P WB
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (clone APA5, PE) LS-C106101

Rat Monoclonal [clone APA5] (IgG2a,k) to Mouse PDGFRA / PDGFR Alpha
Mouse
Flo
PE Conjugated
Anti-PDGFRA / PDGFR Alpha Antibody (phospho-Tyr754) LS-C38277

Rabbit Polyclonal to Human PDGFRA / PDGFR Alpha
Mouse, Human
WB
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody IHC-plus™ LS-B4840

Rabbit Polyclonal to Human PDGFRA / PDGFR Alpha
Human
IHC-P WB
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (C-Terminus) LS-C74981

Rabbit Monoclonal (IgG) to Human PDGFRA / PDGFR Alpha
Mouse, Human
Flo IF IHC-P IP WB
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (clone APA5, Biotin) LS-C106208

Rat Monoclonal [clone APA5] (IgG2a,k) to Mouse PDGFRA / PDGFR Alpha
Mouse
Flo
Biotin Conjugated
Anti-PDGFRA / PDGFR Alpha Antibody (clone 16A1, APC) LS-C112597

Mouse Monoclonal [clone 16A1] (IgG1) to Human PDGFRA / PDGFR Alpha
Human
Flo
APC Conjugated
Anti-PDGFRA / PDGFR Alpha Antibody (aa700-780) LS-C385416

Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Mouse, Rat, Human
ELISA IF IHC WB
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (aa32-324, clone 2E9) IHC-plus™ LS-B14322

Mouse Monoclonal [clone 2E9] (IgG2a) to Human PDGFRA / PDGFR Alpha
Human
IHC-P WB
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (clone 16A1) LS-C112438

Mouse Monoclonal [clone 16A1] (IgG1) to Human PDGFRA / PDGFR Alpha
Human
Flo ICC
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody IHC-plus™ LS-B8655

Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Mouse, Human
IHC-P
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (C-Terminus) IHC-plus™ LS-B2683

Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Mouse, Human
ELISA IHC-P
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (clone APA5, APC) LS-C107240

Rat Monoclonal [clone APA5] (IgG2a,k) to Mouse PDGFRA / PDGFR Alpha
Mouse
Flo
APC Conjugated
Anti-PDGFRA / PDGFR Alpha Antibody LS-C14255

Rat Monoclonal (IgG2a,k) to Mouse PDGFRA / PDGFR Alpha
Mouse
ELISA Flo IHC WB
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody LS-C415937

Rabbit Polyclonal to Human PDGFRA / PDGFR Alpha
Mouse, Rat, Human
ICC IF IHC WB
Unconjugated
Anti-PDGFRA / PDGFR Alpha Antibody (Tyr754, Biotin) LS-C281066

Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Human
ELISA ICC IF IHC WB
Biotin Conjugated
Anti-PDGFRA / PDGFR Alpha Antibody (Tyr754, FITC) LS-C281065

Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Human
ELISA ICC IF IHC WB
FITC Conjugated
Anti-PDGFRA / PDGFR Alpha Antibody (Tyr754, AP) LS-C281063

Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Human
ELISA ICC IF IHC WB
AP Conjugated
Anti-PDGFRA / PDGFR Alpha Antibody (Tyr754, APC) LS-C281064

Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Human
ELISA ICC IF IHC WB
APC Conjugated
Anti-PDGFRA / PDGFR Alpha Antibody (Tyr754, PE) LS-C281069

Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Human
ELISA ICC IF IHC WB
PE Conjugated
Anti-PDGFRA / PDGFR Alpha Antibody (Tyr754, Azide-free, HRP) LS-C281067

Rabbit Polyclonal (IgG) to Human PDGFRA / PDGFR Alpha
Human
ELISA ICC IF IHC WB
HRP Conjugated, Azide-free

Selected:

If you do not find the reagent or information you require, please contact customer.support@lsbio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).


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