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PDE9A

phosphodiesterase 9A

Phosphodiesterase 9A is a cGMP-specific phosphodiesterase. PDE9A activity is inhibited by zaprinast, but it is insensitive to rolipram, vinpocetine, SKF-94120, dipyridamole, and IBMX. More than 20 alternatively spliced variants have been reported (Rentero et al. 2003). PDE9A has been implicated in penile erectile dysfunction, as well as in functional disturbances in which intraneuronal signal transmission via second messengers are important in the pathophysiology (example, bipolar affective disorder). PDE9A is the only cGMP-specific PDE with significant expression in the forebrain, and as such is likely to function in NO-cGMP signaling.

Gene Name: phosphodiesterase 9A
Family/Subfamily: Phosphodiesterase , PDE - cGMP-specific
Synonyms: PDE9A, Pde9A1, Pde9a2, Pde9a3, Pde9a4, Phosphodiesterase 9A, Phosphodiesterase PDE9A21, HSPDE9A2
Target Sequences: NM_002606 NP_002597.1 O76083

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Proteins (30)
Antibodies (17)
ELISA Kits (2)
Over-Expression Lysate (22)
Primary (17)
Recombinant (8)
Sandwich (2)
PDE9A (49)
Human (18)
Mouse (7)
Rat (4)
Chimpanzee (3)
Dog (4)
Gibbon (3)
Monkey (1)
IHC (13)
IHC-P (8)
WB (13)
ELISA (4)
ICC (4)
IF (1)
IP (4)
rabbit (16)
mouse (1)
Product Group
IHCPlus (2)
IgG (10)
IgG2a,k (1)
monoclonal mc (1)
polyclonal pc (16)
1E1 (1)
96-Well Strip Plate (2)
Biotin Conjugated (3)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (2)
HRP Conjugated (2)
Unconjugated (7)
aa136-185 (4)
Internal (1)
aa1-216 (1)
No (49)
Plasma (2)
Serum (2)
GST (1)
GST, N-terminus (1)
His, N-Terminal (1)
His,N-terminus (1)
His-GST (1)
Myc-DDK (Flag) (25)
Human (19)
293T Cells (11)
Baculovirus (1)
E. coli (2)
HEK 293 Cells (14)
Wheat Germ Extract (2)
Purified (2)
Low endotoxin level (1)
PDE9A Antibody - Anti-PDE9A antibody IHC of human spleen. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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PDE9A Rabbit anti-Human Polyclonal (Internal) Antibody
Dog, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
PDE9A Antibody - PDE9A antibody PDE9A(phosphodiesterase 9A) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE9A Rabbit anti-Human Polyclonal (aa136-185) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
PDE9A Antibody - PDE9A antibody PDE9A(phosphodiesterase 9A) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE9A Rabbit anti-Human Polyclonal (aa136-185) (HRP) Antibody
Dog, Human, Chimpanzee, Gibbon
IHC, IHC-P, WB
HRP Conjugated
100 µl/$469
PDE9A Antibody - PDE9A antibody PDE9A(phosphodiesterase 9A) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE9A Rabbit anti-Human Polyclonal (aa136-185) (Biotin) Antibody
Dog, Human, Chimpanzee, Gibbon
IHC, IHC-P, WB
Biotin Conjugated
100 µl/$469
PDE9A Antibody - PDE9A antibody PDE9A(phosphodiesterase 9A) Antibody was used in IHC to stain formalin-fixed, paraffin-embedded human kidney.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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PDE9A Rabbit anti-Human Polyclonal (aa136-185) (FITC) Antibody
Dog, Human, Chimpanzee, Gibbon
IHC, IHC-P, WB
FITC Conjugated
100 µl/$469
PDE9A Antibody - Anti-PDE9A antibody IHC of human adrenal cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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PDE9A Mouse anti-Human Monoclonal (1E1) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
PDE9A Antibody - Immunohistochemistry image at a dilution of 1:600 and staining in paraffin-embedded human adrenal gland tissue performed on a Leica BondTM system. After dewaxing and hydration, antigen retrieval was mediated by high pressure in a citrate buffer (pH 6.0) . Section was blocked with 10% normal goat serum 30min at RT. Then primary antibody (1% BSA) was incubated at 4 °C overnight. The primary is detected by a biotinylated secondary antibody and visualized using an HRP conjugated SP system.
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PDE9A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
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PDE9A Rabbit anti-Human Polyclonal (HRP) Antibody
Human
HRP Conjugated
50 µg/$294; 100 µg/$360
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PDE9A Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
Biotin Conjugated
50 µg/$294; 100 µg/$360
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PDE9A Rabbit anti-Human Polyclonal (FITC) Antibody
Human
FITC Conjugated
50 µg/$294; 100 µg/$360
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PDE9A Rabbit anti-Human Polyclonal (Biotin) Antibody
Mouse, Rat, Human
ICC, IHC, IP, WB
Biotin Conjugated
0.05 ml/$416
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PDE9A Rabbit anti-Human Polyclonal (DY488) Antibody
Mouse, Rat, Human
ICC, IHC, IP, WB
DY488 Conjugated
0.05 ml/$416
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PDE9A Rabbit anti-Human Polyclonal (DY650) Antibody
Mouse, Rat, Human
ICC, IHC, IP, WB
DY650 Conjugated
0.05 ml/$416
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PDE9A Rabbit anti-Human Polyclonal (DY550) Antibody
Mouse, Rat, Human
ICC, IHC, IP, WB
DY550 Conjugated
0.05 ml/$416
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PDE9A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, WB
Unconjugated
100 µg/$331
PDE9A Antibody - IHC of paraffin-embedded N87 xenograft using PDE9A antibody at 1:500 dilution.
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PDE9A Rabbit anti-Human Polyclonal (aa1-216) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$450
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PDE9A Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µl/$412
PDE9A ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PDE9A ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PDE9A Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
PDE9A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
54.3 kDa
20 µg/$215
PDE9A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
53.9 kDa
20 µg/$215
PDE9A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
57.1 kDa
20 µg/$215
PDE9A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
58.8 kDa
20 µg/$215
PDE9A Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
44 kDa
20 µg/$150
Viewing 1-25 of 49 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).