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PDE6G / PDE6 Gamma
phosphodiesterase 6G, cGMP-specific, rod, gamma
PDE6G / PDE6 Gamma is the gamma subunit of cyclic GMP-phosphodiesterase, which is composed of alpha- and beta- catalytic subunits and two identical, inhibitory gamma subunits. This gene is expressed in rod photoreceptors and functions in the phototransduction signaling cascade. It is also expressed in a variety of other tissues, and has been shown to regulate the c-Src protein kinase and G-protein-coupled receptor kinase 2. Alternative splicing results in multiple transcript variants.
| Gene Name: | phosphodiesterase 6G, cGMP-specific, rod, gamma |
| Family/Subfamily: | Phosphodiesterase , PDE - photoreceptor |
| Synonyms: | PDE6G, CGMP-phosphodiesterase gamma, GMP-PDE gamma, PDE6 gamma, Rod cG-PDE G, RP57, PDEG |
| Target Sequences: | NM_002602 NP_002593.1 P18545 |
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