Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Locations


Orders Processing,
Shipping & Receiving,
Warehouse

2 Shaker Rd Suites
B001/B101
Shirley, MA 01464


Production Lab

Floor 6, Suite 620
20700 44th Avenue W
Lynnwood, WA 98036

Telephone Numbers



Tel: +1 (206) 374-1102
Fax: +1 (206) 577-4565

Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

PDE4B

phosphodiesterase 4B, cAMP-specific

PDE4B is a member of the type IV, cyclic AMP (cAMP)-specific, cyclic nucleotide phosphodiesterase (PDE) family. The encoded protein regulates the cellular concentrations of cyclic nucleotides and thereby play a role in signal transduction. Altered activity of this protein has been associated with schizophrenia and bipolar affective disorder. Alternative splicing and the use of alternative promoters results in multiple transcript variants encoding different isoforms.

Gene Name: phosphodiesterase 4B, cAMP-specific
Family/Subfamily: Phosphodiesterase , PDE - cAMP-specific
Synonyms: PDE4B, Pde-ivb, PDE32, PDE4B5, PDEIVB, Phosphodiesterase 4b, DPDE4, PDE4B3
Target Sequences: NM_002600 NP_002591.2 Q07343

Publications (2)

1
Altered phosphorylation, electrophysiology, and behavior on attenuation of PDE4B action in hippocampus. Campbell SL, van Groen T, Kadish I, Smoot LHM, Bolger GB,. BMC neuroscience. 2017 18:77. (WB; Human) [Full Text Article] [PubMed:29197324] Related Antibodies: LS-C173292.
2
PDE4B Is a Homeostatic Regulator of Cyclic AMP in Dendritic Cells. Amy M Chinn, Cristina Salmerón, Jihyung Lee, Krishna Sriram, Eyal Raz, Paul A Insel. Frontiers in pharmacology. 2022 April;13:833832. [Full Text Article] [PubMed:35387344] [PMC:PMC8977838] Related Antibodies: LS-B11018.

☰ Filters
Products
ELISA Kits (5)
Custom (1)
Sandwich (4)
PDE4B (5)
Human (2)
Rat (3)
96-Well Strip Plate (5)
No (5)
Plasma (4)
Serum (4)
Tissue Homogenates (3)
PDE4B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$783
PDE4B ELISA Kit
Select
Custom
96-Well Strip Plate
Human
Colorimetric - 450nm (TMB)
1 Plate/$783
PDE4B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
78 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PDE4B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
PDE4B ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$893
Viewing 1-5 of 5 product results


Filtered By:
Products: ELISA Kits


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).