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PDE1C

phosphodiesterase 1C, calmodulin-dependent 70kDa

Cyclic nucleotide phosphodiesterases (PDEs) catalyze hydrolysis of the cyclic nucleotides cAMP and cGMP to the corresponding nucleoside 5-prime-monophosphates. Mammalian PDEs have been classified into several families based on their biochemical properties. Members of the PDE1 family, such as PDE1C, are calmodulin (see MIM 114180)-dependent PDEs (CaM-PDEs) that are stimulated by a calcium-calmodulin complex (Repaske et al., 1992 [PubMed 1326532]).

Gene Name:	phosphodiesterase 1C, calmodulin-dependent 70kDa
Family/Subfamily:	Phosphodiesterase , PDE - cAMP/cGMP dual-specific, Ca/Calmodulin-dependent
Synonyms:	PDE1C, HCam-3, Hcam3, Phosphodiesterase 1c, Cam-PDE 1C
Target Sequences:	NM_005020 NP_005011.1 Q14123

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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).

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