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PD-L2 / PDCD1LG2 / CD273
programmed cell death 1 ligand 2
Involved in the costimulatory signal, essential for T-cell proliferation and IFNG production in a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation by blocking cell cycle progression and cytokine production.
| Gene Name: | programmed cell death 1 ligand 2 |
| Synonyms: | PDCD1LG2, B7 dendritic cell molecule, B7-DC, B7DC, BA574F11.2, CD273, Btdc, CD273 antigen, PD-L2, PDCD1 ligand 2, PD-1-ligand 2, Programmed death ligand 2, Butyrophilin B7-DC, PD-1 ligand 2, PDCD1L2, PDL2 |
| Target Sequences: | NM_025239 NP_079515.2 Q9BQ51 |
Publications (1)
1
EML4-ALK enhances programmed cell death-ligand 1 expression in pulmonary adenocarcinoma via hypoxia-inducible factor (HIF)-1a and STAT3. Koh J, Jang JY, Keam B, Kim S, Kim MY, Go H, Kim TM, Kim DW, Kim CW, Jeon YK, Chung DH. Oncoimmunology. 2016 5:e1108514. (Flo; Human)
[Full Text Article]
[PubMed:27141364]
☰ Filters
Products
Proteins
(30)
Type
Over-Expression Lysate
(2)
Recombinant
(28)
Target
PD-L2 / PDCD1LG2 / CD273
(30)
Application
Bind
(1)
ELISA
(1)
Func
(1)
SDS-PAGE
(1)
Format
Preservative Free
(1)
Publications
No
(30)
Tag
6His, C-terminus
(1)
DDK (Flag)-His, C-terminus
(1)
Fc, C-terminus
(5)
GST, N-terminus
(1)
His
(2)
His,C-terminus
(4)
His-AVI, C-terminus
(1)
His-T7
(3)
Human IgG1 Fc
(1)
Human Mutant IgG1 Fc
(1)
mFc, C-terminus
(1)
Mouse IgG2 Fc
(2)
Myc-DDK (Flag)
(3)
Species
Crab-eating macaque
(2)
Human
(19)
Mouse
(6)
Rat
(2)
Source
293T Cells
(1)
CHO Cells
(7)
E. coli
(4)
HEK 293 Cells
(8)
Human Cells
(3)
Mammalian Cells
(6)
Wheat Germ Extract
(1)
Purification
Purified
(7)
Low Endotoxin Level
Low endotoxin level
(17)
Biologically Active
Biologically active
(2)
HEK 293 Cells
His,C-terminus
Bind ELISA Func SDS-PAGE
Biologically active
Less than 1.0 EU/µg protein (determined by LAL method).
The recombinant rat PDCD1LG2 comprises 211 amino acids and predicts a molecular mass of 23.9 kDa. The apparent molecular mass of the recombinant protein is approximately 35.7 kDa in SDS-PAGE under reducing conditions.
100 µg/$441
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.59kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
30.8 kDa
20 µg/$1,107
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
24 kDa
100 µg/$502; 1 mg/$3,121
293T Cells
Myc-DDK (Flag)
30.8 kDa
20 µg/$150
E. coli
His-T7
26.8 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
E. coli
His-T7
24.51 kDa
10 µg/$280; 50 µg/$437; 100 µg/$700; 200 µg/$872; 1 mg/$1,978; 500 µg/$1,519; 5 mg/$3,053; 2 mg/$2,164
E. coli
His-T7
31.6 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
Human Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
49.7kD
10 µg/$248; 50 µg/$313; 500 µg/$530; 1 mg/$748
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.5 kDa
10 µg/$265; 50 µg/$368
Human PD-L2 / PDCD1LG2 / CD273 Protein (Recombinant His-AVI, C-terminus) (Leu20-Pro219) - LS-G138366
Mammalian Cells
His-AVI, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
25.4 kDa
20 µg/$416; 100 µg/$910
HEK 293 Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
49.5 kDa
100 µg/$532; 1 mg/$2,785
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
24 kDa
100 µg/$661; 1 mg/$3,499
Mammalian Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
23.59 kDa
10 µg/$317; 50 µg/$524
Mammalian Cells
mFc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
49.2 kDa
10 µg/$281; 50 µg/$389
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
49.5 kDa
10 µg/$288; 50 µg/$436
CHO Cells
None
49 kDa
25 µg/$698
HEK 293 Cells
None
Less than 0.2 EU/µg protein (determined by LAL method).
75 kDa
100 µg/$423; 1 mg/$1,475
HEK 293 Cells
Myc-DDK (Flag)
30.8 kDa
100 µg/$494
Mammalian Cells
Fc, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
49.7 kDa
10 µg/$248; 50 µg/$311
HEK 293 Cells
Fc, C-terminus
50 kDa
20 µg/$1,107
HEK 293 Cells
DDK (Flag)-His, C-terminus
25.3 kDa
20 µg/$1,107
Viewing 1-25
of 30
product results
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