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Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex. Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development.
Gene Name: | Programmed Cell Death 10 |
Synonyms: | PDCD10, Apoptosis-related protein 15, CCM3, Programmed cell death 10, TFAR15 |
Target Sequences: | NM_007217 NP_009148.2 Q9BUL8 |
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